- Methylnissolin
-
- $81.00
-
2026-07-27
- CAS:73340-41-7
- Purity: 99.78%
- Supply Ability: 10g
- Methylnissolin
-
-
2023-02-24
- CAS:73340-41-7
- Min. Order: 10mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
|
| | Methylnissolin Basic information |
| Product Name: | Methylnissolin | | Synonyms: | L-3-Hydroxy-9,10-dimethoxylpterocarpan;Methylnissolin;Medicarpi;3-Hydroxy-9,10-dimethoxyptercarpan,Medicarpin,Methylnissolin;3-Hydroxy-9,10-dimethoxyptercarpanMedicarpin;(-)-6aR,11aR-dihydro-3-hydroxy-9,10-dimethoxy-6H-benzofuro[3,2-c][1]-benzopyran;METHYLNISSOLIN (ASTRAPTEROCARPAN);6H-Benzofuro[3,2-c][1]benzopyran-3-ol, 6a,11a-dihydro-9,10-dimethoxy-, (6aR,11aR)- | | CAS: | 73340-41-7 | | MF: | C17H16O5 | | MW: | 300.31 | | EINECS: | | | Product Categories: | | | Mol File: | 73340-41-7.mol |  |
| | Methylnissolin Chemical Properties |
| Boiling point | 428.9±45.0 °C(Predicted) | | density | 1.312 | | storage temp. | 4°C, protect from light | | solubility | Acetone: soluble; Chloroform: soluble; Dichloromethane: soluble; DMSO: soluble; Ethyl Acetate: soluble | | form | A solid | | pka | 9.44±0.20(Predicted) | | color | White to off-white |
| | Methylnissolin Usage And Synthesis |
| Chemical Properties | It is a white crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO. It is derived from Astragalus membranaceus (Fisch.) Bunge. | | Uses | Methylnissolin (Astrapterocarpan), isolated from Astragalus membranaceus, inhibits platelet-derived growth factor (PDGF)-BB-induced cell proliferation with an IC50 of 10 μM. Methylnissolin inhibits PDGF-BB-induced phosphorylation of extracellular signal-regulated kinase 1/2 (ERIC1/2) mitogen-activated protein (MAP) kinase. Methylnissolin inhibits PDGF-BB-induced vascular smooth muscle cell proliferation by inhibition of the ERK1/2 MAP kinase cascade[1]. | | Definition | ChEBI: Astrapterocarpan is a member of pterocarpans. | | IC 50 | PDGFR: 10 μM (IC50); ERK1; ERK2 | | References | [1] Ohkawara S, et al. Astrapterocarpan isolated from Astragalus membranaceus inhibits proliferation of vascular smooth muscle cells. Eur J Pharmacol. 2005 Nov 21;525(1-3):41-7. DOI:10.1016/j.ejphar.2005.08.063 |
| | Methylnissolin Preparation Products And Raw materials |
|