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| | Boc-aminooxy-PEG3-Propargyl Basic information |
| Product Name: | Boc-aminooxy-PEG3-Propargyl | | Synonyms: | Boc-aminooxy-PEG3-Propargyl;Boc-Aminoxy-PEG3-Alkyne;BOC-AMINOXY-PEG3-PROPARGYL;t-Boc-aminooxy-PEG3-propargyl;3,6,9,12-Tetraoxa-2-azapentadec-14-ynoic acid, 1,1-dimethylethyl ester | | CAS: | 1951439-46-5 | | MF: | C14H25NO6 | | MW: | 303.35 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1951439-46-5.mol |  |
| | Boc-aminooxy-PEG3-Propargyl Chemical Properties |
| density | 1.078±0.06 g/cm3(Predicted) |
| | Boc-aminooxy-PEG3-Propargyl Usage And Synthesis |
| Description | t-Boc-aminooxy-PEG3-propargyl is a click reagent with a propargyl group and t-Boc-aminooxy group. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry. T-Boc-aminooxy group can be free up under mild acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media. | | Uses | N-Boc-aminoxy-PEG3-propargyl is a crosslinker containing a propargyl group and a t-Boc-aminooxy group. N-Boc-aminoxy-PEG3-propargyl can be used in the synthesis of ADC[1]. | | References | [1] Sano K, et al. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. Bioconjug Chem. 2013 May 15;24(5):811-6. DOI:10.1021/bc400050k |
| | Boc-aminooxy-PEG3-Propargyl Preparation Products And Raw materials |
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