N-(m-PEG9)-N'-(PEG5-acid)-Cy5

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Company Name:	Jinan elephant international trading co., LTD
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Email:	13006575422@163.com

Company Name:	Zhengzhou Acme Chemical Co., Ltd.
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Company Name:	Alpha Biopharmaceuticals Co., Ltd
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Company Name:	Nanjing Shizhou Biology Technology Co.,Ltd
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N-(m-PEG9)-N'-(PEG5-acid)-Cy5 Basic information

N-(m-PEG9)-N'-(PEG5-acid)-Cy5 Chemical Properties

solubility

Soluble in Water, DMSO, DMF, DCM

Safety Information

MSDS Information

N-(m-PEG9)-N'-(PEG5-acid)-Cy5 Usage And Synthesis

Description	N-(m-PEG9)-N'-(PEG5-acid)-Cy5 is a near infrared (NIR) fluorescent Cy 5 labeled PEG linker containing free terminal carboxyl acid. Terminal carboxylic acid can react with primary amine groups in the presence of of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydophilic PEG spacer increases solubility in aqueous media. Cy5 labeled PEG linker can be easily traced from its blue color and strong fluorescence.
Uses	N-(m-PEG9)-N'-(PEG5-acid)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50	PEGs
References	[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-(m-PEG9)-N'-(PEG5-acid)-Cy5 Preparation Products And Raw materials

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