| Company Name: |
Energy Chemical |
| Tel: |
400-0056266 |
| Email: |
sales8178@energy-chemical.com |
- 6-Bromopurine
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- $2.00
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2019-07-06
- CAS:767-69-1
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1ton
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| | 6-Bromopurine Basic information |
| | 6-Bromopurine Chemical Properties |
| Melting point | >300 °C (lit.) | | Boiling point | 240.9±50.0 °C(Predicted) | | density | 2.28±0.1 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 7.39±0.20(Predicted) | | color | Pale Beige | | InChI | InChI=1S/C5H3BrN4/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H,7,8,9,10) | | InChIKey | CTGFGRDVWBZYNB-UHFFFAOYSA-N | | SMILES | N1C2C(=NC=NC=2Br)NC=1 |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | RTECS | UO7513000 | | HS Code | 29339900 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 6-Bromopurine Usage And Synthesis |
| Description | 6-Bromopurine is a 6-halogenated purine nucleoside analogue. Studies have shown that 6-halogenopurine inhibits tumour growth when combined with azaserine, which may be related to the blockage of guanine nucleotide biosynthesis. The inhibitory effect of bromopurine occurs between inosine 5‘-phosphate and guanosine 5’-phosphate. 6-Bromopurine also enhances the carcinostatic activity of azaserine. In addition, 6-Bromopurine is also used as an intermediate in the synthesis of Idelalisib. | | Chemical Properties | Dark yellow crystalline powder | | Uses | 6-Bromopurine was used in the synthesis of 6-halopurine alkynes and corresponding triazole derivatives. 6-Bromopurine was used in the synthesis and chemical characterization of 2,3,4,5-tetrahydro-1,5-benzoxazepines-3-ol. | | General Description | 6-Bromopurine enhances the carcinostatic activity of azaserine in a test system employing ascites cell forms of sarcoma 180 and Ehrlich carcinoma in vivo. 6-bromopurine nucleosides are excellent substrates for substitution reactions with N-, O-, and S-containing nucleophiles in polar solvents. |
| | 6-Bromopurine Preparation Products And Raw materials |
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