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| | 2,2-Dibromo-2-cyanoacetamide Basic information |
| | 2,2-Dibromo-2-cyanoacetamide Chemical Properties |
| Melting point | 122-125 °C(lit.) | | Boiling point | 123-126 °C | | density | 2.3846 (rough estimate) | | refractive index | 1.6220 (estimate) | | storage temp. | Inert atmosphere,2-8°C | | Water Solubility | Slightly soluble in water | | solubility | DMSO (Sparingly), Methanol (Slightly) | | pka | 11.72±0.50(Predicted) | | form | powder to crystal | | color | White to Light yellow to Light orange | | Odor | antiseptic odor | | Henry's Law Constant | 5.2×102 mol/(m3Pa) at 25℃, Duchowicz et al. (2020) | | Stability: | Stable, but may be moisture sensitive. Incompatible with strong oxidizing agents. | | Cosmetics Ingredients Functions | ANTIMICROBIAL
PRESERVATIVE | | InChI | 1S/C3H2Br2N2O/c4-3(5,1-6)2(7)8/h(H2,7,8) | | InChIKey | UUIVKBHZENILKB-UHFFFAOYSA-N | | SMILES | NC(=O)C(Br)(Br)C#N | | LogP | 0.820 | | CAS DataBase Reference | 10222-01-2(CAS DataBase Reference) | | EPA Substance Registry System | 2,2-Dibromo-3-nitrilopropionamide (10222-01-2) |
| Hazard Codes | C,Xn | | Risk Statements | 34-43-20/21/22 | | Safety Statements | 26-36/37/39-45-36/37 | | RIDADR | UN 1759 8/PG 3 | | WGK Germany | 3 | | RTECS | AB5956000 | | TSCA | TSCA listed | | HazardClass | 6.1(b) | | PackingGroup | III | | HS Code | 29209090 | | Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | | Hazard Classifications | Acute Tox. 2 Inhalation
Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1
Eye Dam. 1
Skin Irrit. 2
Skin Sens. 1
STOT RE 1 Inhalation | | Hazardous Substances Data | 10222-01-2(Hazardous Substances Data) | | Toxicity | LD50 oral in mammal (species unspecified): 118mg/kg |
| | 2,2-Dibromo-2-cyanoacetamide Usage And Synthesis |
| Description | 2,2-dibromo-3-nitrilopropionamide is a broad-spectrum non-food biocide. It is highly soluble in water and in some organic solvents such as acetone and ethanol. There is little information published on its environmental fate. It is moderately toxic to aquatic organisms. 2,2-dibromo-3-nitrilopropionamide has a moderate human oral toxicity, may be a reproduction/developmental toxin and is a recognised irritant. | | Chemical Properties | white powder | | Uses | A chemical additive to control bacterial contamination in ethanol fermentation. | | Production Methods | The commercial production of 2,2-dibromo-3-nitrilopropionamide (DBNPA) involves the bromination of cyanoacetamide in an aqueous medium. In this process, bromine is added to cyanoacetamide, resulting in the formation of DBNPA and hydrobromic acid. To improve bromine utilization and reduce costs, sodium hypochlorite is introduced as an oxidant to regenerate bromine from the hydrobromic acid, allowing further bromination. The reaction is conducted at 10–20 DegC to control exothermicity and prevent decomposition. | | General Description | Colorless to yellow liquid with a moldy pungent odor. | | Air & Water Reactions | Water soluble. | | Reactivity Profile | 2,2-Dibromo-2-cyanoacetamide is incompatible with bases, metals, oxidizing agents, acids. Dangerous gases may accumulate as a result of ignition and fire. | | Mechanism of action | Broad-spectrum antimicrobial activity | | Safety Profile | Poison by ingestion and
intravenous routes. A severe skin and eye
irritant. When heated to decomposition it
emits very toxic fumes of Brand NO,. See
also NITRILES. | | Pesticide Type | Fungicide; Algicide |
| | 2,2-Dibromo-2-cyanoacetamide Preparation Products And Raw materials |
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