- H-PHE-NH2
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- $2.00 / 1KG
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2020-01-10
- CAS:5241-58-7
- Min. Order: 1g
- Purity: 98%MIN
- Supply Ability: ASK
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| | H-PHE-NH2 Basic information |
| | H-PHE-NH2 Chemical Properties |
| Melting point | 93-95°C | | Boiling point | 356.9±35.0 °C(Predicted) | | density | 1.143±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | pka | 15.85±0.50(Predicted) | | form | Powder | | color | White | | Optical Rotation | Consistent with structure | | BRN | 6270941 | | CAS DataBase Reference | 5241-58-7(CAS DataBase Reference) |
| WGK Germany | 3 | | HazardClass | IRRITANT |
| | H-PHE-NH2 Usage And Synthesis |
| Chemical Properties | Off-White Solid | | Uses | Protected amino acid | | Definition | ChEBI: An amino acid amide derived from L-phenylalanine. | | Biological Activity | L-Phenylalaninamide is a chiral selector. | | Synthesis | General procedure for the synthesis of (S)-2-amino-3-phenylpropionamide from L-phenylalanine methyl ester hydrochloride: intermediate 1 (L-phenylalanine methyl ester hydrochloride) was dissolved in 20% aqueous ammonia solution and the reaction was stirred for 20 hours at room temperature. Upon completion of the reaction, 50 mL of ethyl acetate was added to the reaction mixture and three extraction operations were performed. All organic phases were combined and the solvent was removed by rotary evaporator to afford Intermediate 2 ((S)-2-amino-3-phenylpropionamide) as a white solid in 2.5 g yield, 76%. | | References | [1] Helvetica Chimica Acta, 2004, vol. 87, # 5, p. 1077 - 1089
[2] Organic and Biomolecular Chemistry, 2012, vol. 10, # 30, p. 6074 - 6086
[3] Chemistry - An Asian Journal, 2011, vol. 6, # 6, p. 1321 - 1324
[4] Bulletin de la Societe Chimique de France, 1989, # 5, p. 673 - 676
[5] Patent: CN108610292, 2018, A. Location in patent: Paragraph 0041; 0051; 0052 |
| | H-PHE-NH2 Preparation Products And Raw materials |
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