H-Phe-NH2

H-Phe-NH2 Suppliers list

Company Name:	Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel:	4006356688 18621169109
Email:	market03@meryer.com

Company Name:	BeiJing Hwrk Chemicals Limted
Tel:	0757-86329057 18934348241
Email:	sales4.gd@hwrkchemical.com

H-Phe-NH2 manufacturers

H-Phe-NH2 Basic information

Product Name:	H-Phe-NH2
Synonyms:	H-L-PHE-NH2;L-PHENYLALANINAMIDE;PHENYLALANINE-NH2;L-Phe-NH2;2-Amino-3-phenylpropanamide H-Phe-NH2;H-Phe-NH2 (HPLC);L-phenylalaninamide free base;H-Phe-Nh
CAS:	5241-58-7
MF:	C9H12N2O
MW:	164.2
EINECS:
Product Categories:	Amino Acids & Derivatives;Aromatics;Chiral Reagents;Phenylalanine [Phe, F];Amino Acids and Derivatives;Amino Acid Derivatives;Peptide Synthesis;Phenylalanine;Amino Acids;I - Z;Modified Amino Acids
Mol File:	5241-58-7.mol

H-Phe-NH2 Chemical Properties

Melting point	93-95°C
Boiling point	356.9±35.0 °C(Predicted)
density	1.143±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka	15.85±0.50(Predicted)
form	Powder
color	White
Optical Rotation	Consistent with structure
BRN	6270941
Major Application	detection
InChI	1S/C9H12N2O/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H2,11,12)/t8-/m0/s1
InChIKey	OBSIQMZKFXFYLV-QMMMGPOBSA-N
SMILES	N[C@@H](Cc1ccccc1)C(N)=O
CAS DataBase Reference	5241-58-7(CAS DataBase Reference)

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English

H-Phe-NH2 Usage And Synthesis

Chemical Properties	Off-White Solid
Uses	Protected amino acid
Definition	ChEBI: An amino acid amide derived from L-phenylalanine.
Biological Activity	L-Phenylalaninamide is a chiral selector.
Synthesis	7524-50-7 5241-58-7 General procedure for the synthesis of (S)-2-amino-3-phenylpropionamide from L-phenylalanine methyl ester hydrochloride: intermediate 1 (L-phenylalanine methyl ester hydrochloride) was dissolved in 20% aqueous ammonia solution and the reaction was stirred for 20 hours at room temperature. Upon completion of the reaction, 50 mL of ethyl acetate was added to the reaction mixture and three extraction operations were performed. All organic phases were combined and the solvent was removed by rotary evaporator to afford Intermediate 2 ((S)-2-amino-3-phenylpropionamide) as a white solid in 2.5 g yield, 76%.
References	[1] Helvetica Chimica Acta, 2004, vol. 87, # 5, p. 1077 - 1089 [2] Organic and Biomolecular Chemistry, 2012, vol. 10, # 30, p. 6074 - 6086 [3] Chemistry - An Asian Journal, 2011, vol. 6, # 6, p. 1321 - 1324 [4] Bulletin de la Societe Chimique de France, 1989, # 5, p. 673 - 676 [5] Patent: CN108610292, 2018, A. Location in patent: Paragraph 0041; 0051; 0052

H-Phe-NH2 Preparation Products And Raw materials

Raw materials	methyl 3-phenyl-L-alaninate-->Methyl L-phenylalaninate hydrochloride
Preparation Products	Nalpha-Cbz-L-Arginine-->N-Cbz-L-Leucine-->(1-amino-3-phenylpropan-2-yl)(methyl)amine

Tag:H-Phe-NH2(5241-58-7) Related Product Information

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