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Butanoic acid, 4-(2-pyridinyldithio)-2-sulfo-, 1-(2,5-dioxo-1-pyrrolidinyl) ester manufacturers
- sulfo-SPDB
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2025-06-07
- CAS:1193111-39-5
- Min. Order: 5mg
- Purity: >95.00%
- Supply Ability: 5mg
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| | Butanoic acid, 4-(2-pyridinyldithio)-2-sulfo-, 1-(2,5-dioxo-1-pyrrolidinyl) ester Basic information |
| | Butanoic acid, 4-(2-pyridinyldithio)-2-sulfo-, 1-(2,5-dioxo-1-pyrrolidinyl) ester Chemical Properties |
| density | 1.66±0.1 g/cm3(Predicted) | | storage temp. | -80°C, protect from light, stored under nitrogen | | solubility | Soluble in DMSO | | pka | -0.08±0.50(Predicted) | | form | Solid | | color | Off-white to yellow |
| | Butanoic acid, 4-(2-pyridinyldithio)-2-sulfo-, 1-(2,5-dioxo-1-pyrrolidinyl) ester Usage And Synthesis |
| Uses | sulfo-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | | IC 50 | Disulfide Cleavable Linker; Cleavable Linker | | References | [1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268 |
| | Butanoic acid, 4-(2-pyridinyldithio)-2-sulfo-, 1-(2,5-dioxo-1-pyrrolidinyl) ester Preparation Products And Raw materials |
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