| Company Name: |
Sigma-Aldrich |
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
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| | HUMAN TNF-ALPHA Basic information |
| Product Name: | HUMAN TNF-ALPHA | | Synonyms: | REC TNF-A (HUMAN);CACHECTIN;HTNF-ALPHA;HUMAN DIFFERENTIATION-INDUCING FACTOR;HUMAN DIF;HUMAN CYTOTOXIN;HUMAN CACHECTIN;HUMAN NECROSIN | | CAS: | 94948-61-5 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![HUMAN TNF-ALPHA Structure]() |
| | HUMAN TNF-ALPHA Chemical Properties |
| storage temp. | −20°C | | form | powder |
| RIDADR | UN 3264 8 / PGIII | | WGK Germany | 3 | | RTECS | MT6435000 | | Storage Class | 8A - Combustible corrosive hazardous materials | | Hazard Classifications | Met. Corr. 1 |
| | HUMAN TNF-ALPHA Usage And Synthesis |
| Uses | For research use only. Not for use in diagnostic procedures.
Rat Tumor Necrosis Factor α ELISA Kit has been used to measure rat tumor necrosis-α (TNF-α) in cell lysate and tissue lysate. | | General Description | The Rat TNF-α ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Rat TNF-α in serum, plasma, cell culture supernatants and urine. | | Biochem/physiol Actions | Tumor necrosis factor-α (TNF-α) affects various cellular processes such as blood-brain barrier, inflammatory, thrombogenic, and vascular changes following brain damage. TNF-α expression is upregulated in various central nervous system disorders, including Alzheimer′s disease, multiple sclerosis, Parkinson′s disease, meningococcal meningitis and HIV infection. Elevated expression of TNF-α in brain and blood in response to lipopolysaccharide might increase brain stem thrombosis and hemorrhage and stroke sensitivity/risk in hypertensive rats. Tumor necrosis factor-α activates polymorphonuclear leukocyte NADPH oxidase, thereby facilitates development of systemic oxidative stres (OS), inflammation and hypertension in rats. |
| | HUMAN TNF-ALPHA Preparation Products And Raw materials |
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