- 2-Picoline-N-oxide
-
- $100.00 / 1KG
-
2026-02-27
- CAS:931-19-1
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 5MT per month
- 2-Picoline-N-oxide
-
- $1.00 / 1KG
-
2019-07-06
- CAS:931-19-1
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 100KG
|
| | 2-Picoline-N-oxide Basic information |
| Product Name: | 2-Picoline-N-oxide | | Synonyms: | 2-PICOLINE-N-OXIDE 95%(MIN);2-Methylpyridine-N-oxide hemihydrate(2-Picoline-N-oxide hemihydrate);Alpha-picoline N-oxide, 2-Picoline N-oxide;2-Methyl-1-oxidopyridin-1-ium;a-Picoline 1-oxide;a-Picoline N-oxide;1-Oxylato-2-methylpyridinium;2-Picoline-N-oxide,98% | | CAS: | 931-19-1 | | MF: | C6H7NO | | MW: | 109.13 | | EINECS: | 213-230-3 | | Product Categories: | Pyridines;Pyridine;bc0001 | | Mol File: | 931-19-1.mol |  |
| | 2-Picoline-N-oxide Chemical Properties |
| Melting point | 41-45 °C(lit.) | | Boiling point | 259-261 °C | | density | 1.1143 (rough estimate) | | refractive index | 1.5444 (estimate) | | Fp | >230 °F | | storage temp. | RT, stored under nitrogen | | pka | pK1:1.029(+1) (25°C) | | form | powder to lump to clear liquid | | color | White or Colorless to Light yellow | | Water Solubility | soluble | | Sensitive | Hygroscopic | | BRN | 106916 | | InChI | InChI=1S/C6H7NO/c1-6-4-2-3-5-7(6)8/h2-5H,1H3 | | InChIKey | CFZKDDTWZYUZKS-UHFFFAOYSA-N | | SMILES | C1(C)[N+]([O-])=CC=CC=1 | | CAS DataBase Reference | 931-19-1(CAS DataBase Reference) | | NIST Chemistry Reference | Pyridine, 2-methyl-, 1-oxide(931-19-1) | | EPA Substance Registry System | 2-Methylpyridine-1-oxide (931-19-1) |
| Hazard Codes | Xi,Xn,F | | Risk Statements | 36/37/38-20/21/22-10 | | Safety Statements | 26-36-24/25-16 | | WGK Germany | 3 | | F | 3 | | TSCA | TSCA listed | | HS Code | 29333990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 2-Picoline-N-oxide Usage And Synthesis |
| Chemical Properties | light yellow to brown crystalline low melting mass | | Uses | 2-Picoline N-oxide is used in proteomics research. Also used as pharmaceutical intermediates. | | Application | 2-Methylpyridine 1-oxide is a useful building block for organic synthesis. | | Definition | ChEBI: Picoline N-oxide is a member of methylpyridines and a member of pyridine N-oxides. | | Synthesis | K2CO3 (20 mmol) and urea peroxide (10 mmol) were dissolved in dry 1,4-dioxane (100 mL), which was then stirred and reacted at room temperature for 1 hour. Trifluoroacetic anhydride (10 mmol) was added dropwise to the mixture below 12 C to bring the mixture back to room temperature. To the reaction mixture was added the corresponding 2-methylpyridine (1 mmol) and the mixture was stirred at 50 C overnight. The 1,4-dioxane was removed by distillation and replaced with dichloromethane, the mixture was washed with water (50 mL) and the resulting organic layer was dried over anhydrous MgSO4, filtered to remove the desiccant and the resulting filtrate was concentrated under vacuum to remove the solvent to give the 2-methylpyridine oxide. | | Purification Methods | Purify the N-oxide by fractional distillation, and it can be recrystallised from *C6H6/hexane but is hygroscopic. [Bullitt & Maynard J Am Chem Soc 76 1370 1954, Ross et al. J Am Chem Soc 78 3625 1956, IR: Wiley & SlaymAker J Am Chem Soc 79 2233 1957.] The picrate has m 125-126.5o (from EtOH) [Boekelheide & Linn J Am Chem Soc 76 1286 1954]. The phthalate has m 115-116o (from EtOH) [den Hertog et al. Recl Trav Chim Pays-Bas 70 591 1951.]. [Beilstein 20 III/IV 2689, 20/5 V 479.] |
| | 2-Picoline-N-oxide Preparation Products And Raw materials |
|