| Company Name: |
ChemeGen |
| Tel: |
18818260767 |
| Email: |
2625930290@qq.com |
|
| | C18 D-threo Ceramide (d18:1/18:0) Basic information |
| Product Name: | C18 D-threo Ceramide (d18:1/18:0) | | Synonyms: | C18 D-threo Ceramide (d18:1/18:0);Octadecanamide, N-[(1R,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-;N-[(1R,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-octadecanamide | | CAS: | 252039-53-5 | | MF: | C36H71NO3 | | MW: | 565.95 | | EINECS: | | | Product Categories: | | | Mol File: | 252039-53-5.mol |  |
| | C18 D-threo Ceramide (d18:1/18:0) Chemical Properties |
| Boiling point | 694.5±55.0 °C(Predicted) | | density | 0.915±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | pka | 13.54±0.20(Predicted) | | form | A solid |
| | C18 D-threo Ceramide (d18:1/18:0) Usage And Synthesis |
| Uses | C18 D-threo ceramide (d18:1/18:0) is a biochemical reagent. | | Biological Activity | C18 D-threo Ceramide (d18:1/18:0) is a synthetic ceramide and stereoisomer of C18 ceramide .1 It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50 value of 16.6 μM.2 [Matreya, LLC. Catalog No. 1855] | | References | 1.Koolath, S., Murai, Y., Suga, Y., et al.Chiral combinatorial preparation and biological evaluation of unique ceramides for inhibition of sphingomyelin synthaseChirality32(3)308-313(2019)
2.Usta, J., El Bawab, S., Roddy, P., et al.Structural requirements of ceramide and sphingosine based inhibitors of mitochondrial ceramidaseBiochemistry40(32)9657-9668(2001) |
| | C18 D-threo Ceramide (d18:1/18:0) Preparation Products And Raw materials |
|