| Company Name: |
Energy Chemical |
| Tel: |
400-0056266 |
| Email: |
sales8178@energy-chemical.com |
- 2-Quinazolinamine
-
- $1.00
-
2020-01-10
- CAS:1687-51-0
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 200kg
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| | 2-Quinazolinamine Basic information |
| Product Name: | 2-Quinazolinamine | | Synonyms: | 2-Quinazolinamine (9CI);2-Aminoquinazoline;2-Quinazolinamine;Quinazolin-2-ylamine;Quinazoline, 2-amino-;2-Aminoquinazoline, CAS 1687-51-0;quinazolin-2-amine - [Q83533];quinazolin-2-amine | | CAS: | 1687-51-0 | | MF: | C8H7N3 | | MW: | 145.16 | | EINECS: | | | Product Categories: | PYRIMIDINE | | Mol File: | 1687-51-0.mol |  |
| | 2-Quinazolinamine Chemical Properties |
| Melting point | 204 °C | | Boiling point | 370.7±25.0 °C(Predicted) | | density | 1.292±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | form | solid | | pka | 4.86±0.10(Predicted) | | color | Yellow | | NIST Chemistry Reference | 2-Quinazolinamine(1687-51-0) |
| | 2-Quinazolinamine Usage And Synthesis |
| Synthesis | GENERAL STEPS: DMSO (2.0 mL) was added to a 25 mL Schlenk tube protected by nitrogen and equipped with a magnetic stirrer. 2-Bromobenzylamine (1) (0.5 mmol), guanidine hydrochloride (2) (1.0 mmol), CuBr (0.1 mmol, 14.2 mg) and K2CO3 (1.5 mmol, 207 mg) were added sequentially. The reaction mixture was stirred at 80-120 °C for 24 h, followed by continued stirring for 0.5 h in air. After completion of the reaction, the mixture was cooled to room temperature, filtered, and the solid fraction was washed with ethyl acetate (3 x 3 mL). The filtrates were combined and concentrated by rotary evaporator and the residue was purified by silica gel column chromatography using petroleum ether/ethyl acetate as eluent to give the target product 2-aminoquinazoline. | | References | [1] Synlett, 2013, vol. 24, # 16, p. 2089 - 2094 |
| | 2-Quinazolinamine Preparation Products And Raw materials |
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