Etoxadrol

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Company Name: Zhejiang J&C Biological Technology Co.,Limited  
Tel: +1-2135480471
Email: sales@sarms4muscle.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

Etoxadrol manufacturers

  • Etoxadrol
  • Etoxadrol pictures
  • $1980.00
  • 2026-05-11
  • CAS:28189-85-7
  • Purity:
  • Supply Ability: 10g
Etoxadrol Basic information
Product Name:Etoxadrol
Synonyms:Etoxadrol;(S)-2-[(2S)-2-Ethyl-2α-phenyl-1,3-dioxolan-4β-yl]piperidine;Nsc288020;Piperidine, 2-(2-ethyl-2-phenyl-1,3-dioxolan-4-yl)-;Piperidine, 2-(2-ethyl-2-phenyl-1,3-dioxolan-4-yl)-, (+)-;Piperidine, 2-[(2S,4S)-2-ethyl-2-phenyl-1,3-dioxolan-4-yl]-, (2S)-
CAS:28189-85-7
MF:C16H23NO2
MW:261.36
EINECS:
Product Categories:
Mol File:28189-85-7.mol
Etoxadrol Structure
Etoxadrol Chemical Properties
Boiling point 404.61°C (rough estimate)
density 1.0086 (rough estimate)
refractive index 1.5500 (estimate)
pka9.57±0.10(Predicted)
Water Solubility 0.65g/L(20 ºC)
Safety Information
MSDS Information
Etoxadrol Usage And Synthesis
UsesEtoxadrol (CL-1848C) is a potent, high-affinity N-methyl-D-aspartic acid (NMDA) antagonist. Etoxadrol is used in the anaesthetic and anaesthesia research community to suppress or relieve pain[1].
in vivo

Etoxadrol (CL-1848C) (100.0 mg/kg; i.h.; once) produces marked stimulation and ataxia in mice[2].
Etoxadrol (0-20 mg/kg; i.v.; once) decreases brain monoamine concentrations after 4 h injection[3].

Animal Model:Carworth-Farm (Upjohn) male mice weighing 18 to 20 gm[2]
Dosage:100.0 mg/kg
Administration:Subcutaneous injection, 30 min
Result:Produced marked stimulation and ataxia.
Animal Model:Male CFE rats weighing 110-175 g (average 130 g)[3]
Dosage:5, 10, and 20 mg/kg
Administration:Intravenous injection, once
Result:Significantly lowered brain serotonin, DA (dopamine), and NE (norepinephrine) concentrations at 4 h.
References[1] A Thurkauf, et al. Synthesis, absolute configuration, and molecular modeling study of etoxadrol, a potent phencyclidine-like agonist. J Med Chem. 1988 Dec;31(12):2257-63. DOI:10.1021/jm00120a004
[2] A H Tang, et al. Analgetic activities of etoxadrol in the rhesus monkey and in mice. Anesth Analg. 1973 Jul-Aug;52(4):577-83. PMID:4197876
[3] Y F Sung, et al. Effects of intravenous anesthetics on brain monoamines in the rat. Anesthesiology. 1973 Nov;39(5):478-87. DOI:10.1097/00000542-197311000-00004
Etoxadrol Preparation Products And Raw materials
Tag:Etoxadrol(28189-85-7) Related Product Information
(2,2-Dimethyl-[1,3]-dioxolan-4-yl)-methylamine Etoxadrol DHEA-S CNQX D-Serine Evans Blue