2,3-Dimethoxybenzylamine manufacturers
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| | 2,3-Dimethoxybenzylamine Basic information |
| Product Name: | 2,3-Dimethoxybenzylamine | | Synonyms: | RARECHEM AL BW 0151;2,3-DIMETHOXYBENZYLAMINE;2,3-Dimethoxybenzylamine ,99%;2,3-Dimethoxybenzyla;(2,3-Dimethoxyphenyl)methylamine;2,3-Dimethoxybenzylamine 99%;2,3-Dimethoxybenzenemethanamine;2,3-Dimethoxybenzylamine> | | CAS: | 4393-09-3 | | MF: | C9H13NO2 | | MW: | 167.21 | | EINECS: | 224-515-7 | | Product Categories: | Amines;C9 to C10;Nitrogen Compounds;Anilines, Aromatic Amines and Nitro Compounds;Amine | | Mol File: | 4393-09-3.mol |  |
| | 2,3-Dimethoxybenzylamine Chemical Properties |
| Melting point | 229-230 °C(Solv: N,N-dimethylformamide (68-12-2)) | | Boiling point | 137 °C/11 mmHg (lit.) | | density | 1.13 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.54(lit.) | | Fp | >230 °F | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | pka | 9.12±0.10(Predicted) | | form | Liquid | | color | Clear colorless to pale yellow | | CAS DataBase Reference | 4393-09-3(CAS DataBase Reference) | | NIST Chemistry Reference | Benzenemethanamine, 2,3-dimethoxy-(4393-09-3) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39 | | RIDADR | 2735 | | WGK Germany | 3 | | HazardClass | IRRITANT | | PackingGroup | III | | HS Code | 29222900 |
| | 2,3-Dimethoxybenzylamine Usage And Synthesis |
| Chemical Properties | Colorless to light yellowliqui | | Uses | 2,3-Dimethoxybenzylamine was used in the synthesis of di-,tri- and tetrapeptide linked dicatechol derivatives and 1-aryl-2,3-dihydro-1H-isoindoles (isoindolines). | | Synthesis | Add 14.0g of anhydrous zinc chloride, 11.0g of potassium borohydride and 150ml of tetrahydrofuran into a 500ml round bottom flask, protected by nitrogen, stirred at room temperature for 2.5 hours, add 60ml of toluene and 13.0g of 2,3-dimethoxybenzoic acid amine, evaporate part of the solvent with heat and react at 100 for 3.5 hours, after cooling, pour into 150mL of 10% hydrochloric acid, then dropwise add 10% potassium hydroxide solution to pH 11, filtered, the filtrate was extracted with ether (20 ml), the extracts were combined, dried with anhydrous sodium sulfate, evaporated off the ether, distilled under reduced pressure, and 6.72 g of the fractions at 151~152.5 C/13 mmHg were collected, 71.9% yield of 2,3-dimethoxybenzylamine. |
| | 2,3-Dimethoxybenzylamine Preparation Products And Raw materials |
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