polymyxin B(1) manufacturers
- polymyxin B(1)
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- $1.00
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2026-08-07
- CAS:4135-11-9
- Min. Order: 1KG
- Purity: 99%+
- Supply Ability: 10086KG
- Polymyxin B1
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- $1080.00
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2026-04-21
- CAS:4135-11-9
- Purity:
- Supply Ability: 10g
- Polymyxin B1
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-
2025-12-19
- CAS:4135-11-9
- Min. Order: 5mg
- Purity: 85~95%
- Supply Ability: 100mg
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| | polymyxin B(1) Basic information |
| Product Name: | polymyxin B(1) | | Synonyms: | (6S)-N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methyloctanamide;polymyxin B(1);(-)-N2-[[(6S)-6-Methyloctanoyl]-L-A2bu-L-Thr-L-A2bu-]cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-);polymyxin B1Q: What is
polymyxin B1 Q: What is the CAS Number of
polymyxin B1;(S)-N-((S)-4-amino-1-(((2S,3R)-1-(((S)-4-amino-1-oxo-1-(((3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-((R)-1-hydroxyethyl)-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino)-3-hydroxy-1-oxobutan-2-yl)amino)-1-oxobutan-2-yl)-6-methyloctanamide;Polymyxin B1-[13C6,15N] TFA salt;Glucosamine Hydrochloride Impurity 33 | | CAS: | 4135-11-9 | | MF: | C56H98N16O13 | | MW: | 1203.48 | | EINECS: | | | Product Categories: | | | Mol File: | 4135-11-9.mol |  |
| | polymyxin B(1) Chemical Properties |
| Boiling point | 838.79°C (rough estimate) | | density | 1.0500 (rough estimate) | | refractive index | 1.6200 (estimate) | | storage temp. | Store at -20°C | | solubility | PBS (pH 7.2): 2 mg/ml | | form | A crystalline solid | | pka | 13.08±0.70(Predicted) | | color | White to off-white | | Sequence | {Dab(6-methyl-1-oxooctyl)}-Thr-{Dab}-{Dab}-{Dab}-{d-Phe}-Leu-{Dab}-{Dab}-Thr (Lactam bridge: Dab4-Thr10) | | InChIKey | WQVJHHACXVLGBL-CTMZAJDNSA-N |
| | polymyxin B(1) Usage And Synthesis |
| Uses | An antibacterial compound. It has a high volume of distribution and longer elimination half-life in patient with multidrug-resistant gram-negative bacterial infection. | | Definition | ChEBI: A polymyxin having a (6R)-6-methyloctanoyl group at the amino terminus. | | in vivo | The pharmacokinetics of Polymyxin B1 is investigated in a rat model following intravenous administration (0.8 mg/kg). The area under the concentration-time curve for Polymyxins B1 is greater than those of colistins A and B. Colistin A colistin B. The clearance value of Polymyxins B1 is 2.39 mL/min/kg, the plasma protein binding is 82.3%, the elimination half-life is 79.5 min and the AUC0-∞ is 365 mg min/L[5]. |
| | polymyxin B(1) Preparation Products And Raw materials |
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