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3-Bromo-7-nitroindazole

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3-Bromo-7-nitroindazole manufacturers
3-Bromo-7-nitroindazole Basic information
Product Name:3-Bromo-7-nitroindazole
Synonyms:3-BroMo-7-nitro-1H-indazo...;1H-INDAZOLE,3-BROMO-7-NITRO-;7-NITROINDAZOLE, 3-BROMO-;3-Bromo-7-nitroindazole, 98+%;3-Bromo-7-nitroindaz;3-Bromo-7-nitroindazole, 10 mM in DMSO;3-BROMO-7-NITRO-1H-INDAZOLE;BRNI
CAS:74209-34-0
MF:C7H4BrN3O2
MW:242.03
EINECS:
Product Categories:Nitric Oxide Synthase (iNOS)Enzyme Inhibitors by Enzyme;Nitric Oxide Synthase neuronalNitric Oxide and Cell Stress;Enzyme Inhibitors by Enzyme;L to;Nitric Oxide Metabolism;Nitric Oxide Synthase RegulatorsCell Signaling Enzymes;NOS Inhibitors;Nitric Oxide;Indoles and derivatives;All Inhibitors;Inhibitors;Nitric Oxide Reagents
Mol File:74209-34-0.mol
3-Bromo-7-nitroindazole Structure
3-Bromo-7-nitroindazole Chemical Properties
Melting point 175-185 °C
Boiling point 182°C
density 1.8856 (rough estimate)
refractive index 1.6200 (estimate)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility ethanol: 25 mg/mL
form powder
pka7.85±0.40(Predicted)
color light yellow
Sensitive Light Sensitive
InChIInChI=1S/C7H4BrN3O2/c8-7-4-2-1-3-5(11(12)13)6(4)9-10-7/h1-3H,(H,9,10)
InChIKeyNFSTZPMYAZRZPC-UHFFFAOYSA-N
SMILESN1C2=C(C=CC=C2[N+]([O-])=O)C(Br)=N1
CAS DataBase Reference74209-34-0(CAS DataBase Reference)
Safety Information
Hazard Codes T
Risk Statements 60
Safety Statements 53-22-36/37/39-45
WGK Germany 3
Hazard Note Harmful to reproduction
HazardClass IRRITANT
HS Code 2933998090
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
3-Bromo-7-nitroindazole Usage And Synthesis
Chemical PropertiesYellow Crystals
UsesA more potent inhibitor of rat cerebellar nitric oxide synthase than 7-nitroindazole
UsesInhibitor of nitric oxide synthase (NOS)
Uses3-Bromo-7-nitroindazole is a potent and selective neuronal nitric oxide synthase (nNOS) inhibitor (1,2). It is also a neuroprotective compound that inhibits the endoplasmic reticulum stress pathway. 3-Bromo-7-nitroindazole has been used to study the role of nitric oxide synthase (nNOS) in spatial memory formation in rats (2).
IC 50nNOS
storageDesiccate at +4°C
3-Bromo-7-nitroindazole Preparation Products And Raw materials
Tag:3-Bromo-7-nitroindazole(74209-34-0) Related Product Information
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