- ABSINTHIN
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- $9.80
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2020-01-10
- CAS:1362-42-1
- Min. Order: 1KG
- Purity: ≥98%
- Supply Ability: 20 tons
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| | ABSINTHIN Basic information |
| Product Name: | ABSINTHIN | | Synonyms: | ABSINTHIN;ABSYNTHIN;ABSINTHII TINCTURA;Absynthine;Absinthiin;Sbsinthin;2H-7,13b-Ethenopentaleno[1'',2'':6,7;5'',4'':6',7']dicyclohepta[1,2-b:1',2'-b']difuran-2,12(11H)-dione,3,3a,4,5,6,6a,6b,7,7a,8,9,10,10a,13a,13c,14b-hexadecahydro-6,8-dihydroxy-3,6,8,11,14,15-hexamethyl-,(3S,3aS,6S,6aR,6bS,7S,7aR,8S,10aS,11S,13aS,13bR,13cR | | CAS: | 1362-42-1 | | MF: | C30H40O6 | | MW: | 496.64 | | EINECS: | | | Product Categories: | Miscellaneous Natural Products | | Mol File: | 1362-42-1.mol |  |
| | ABSINTHIN Chemical Properties |
| Melting point | 165-166℃ (dec.) | | alpha | D20 +107.0° (c = 1.9 in CHCl3); D20 +103.5° (c = 1.0 in CHCl3) | | Boiling point | 700.6±60.0 °C(Predicted) | | density | 1.29±0.1 g/cm3 (20 ºC 760 Torr) | | storage temp. | Amber Vial, -20°C Freezer, Under inert atmosphere | | solubility | Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 14.66±0.70(Predicted) | | color | White to Off-White | | Water Solubility | insoluble in water | | Stability: | Light Sensitive, Unstable in Acidic Condition | | InChIKey | PZHWYURJZAPXAN-ILOFNVQHSA-N | | SMILES | O1[C@@H]2[C@@]43[C@@H]([C@@H]([C@H]5[C@@H]4C(=C6[C@H]7OC(=O)[C@H]([C@@H]7CC[C@@]([C@@H]65)(O)C)C)C)C=C3C)[C@](CC[C@H]2[C@@H](C1=O)C)(O)C |
| WGK Germany | WGK 3 | | HS Code | 29329990 | | Storage Class | 11 - Combustible Solids |
| | ABSINTHIN Usage And Synthesis |
| Uses | Absinthin is an extract from the bitter liquor Absinthe, which owes its taste to substances found in the wormwood plant used in its formulation. Absinthin contributes to this bitter taste through action upon the hTAS2R14 bitter taste receptor. | | Definition | ChEBI: A dimeric sesquiterpene lactone that is produced by the plant Artemisia absinthium (Wormwood). The bitter tasting constituent of Absinthe. | | in vivo | Absinthin (20-80mg/kg, p.o.) relieves LPS-induced acute lung injury (reduces inflammatory cell infiltration and improves
lung architecture) in mice[4].
| Animal Model: | LPS-induced acute lung injury in mice[4] | | Dosage: | 20, 40, 80mg/kg | | Administration: | p.o. | | Result: | Reduced inflammatory cell infiltration and improved lung architecture.
Reduced MPO activity, infiltration of neutrophils, lung tissue wet-to-dry ratio.
Reduced the secretion of proinflammatory cytokines and chemokines (TNF-α, IL-1β, IL-6
, and MIP-1α). |
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| | ABSINTHIN Preparation Products And Raw materials |
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