2-(BOC-AMINO)ETHANETHIOL manufacturers
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| | 2-(BOC-AMINO)ETHANETHIOL Basic information |
| | 2-(BOC-AMINO)ETHANETHIOL Chemical Properties |
| Boiling point | 68 °C0.3 mm Hg(lit.) | | density | 1.049 g/mL at 20 °C(lit.) | | refractive index | n20/D 1.474(lit.) | | Fp | >230 °F | | storage temp. | Hygroscopic, Refrigerator, under inert atmosphere | | solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly) | | pka | 9.95±0.10(Predicted) | | form | Viscous Liquid or Low Melting Solid | | Specific Gravity | 1.049 | | color | Clear colorless to yellow | | BRN | 2243173 | | InChI | InChI=1S/C7H15NO2S/c1-7(2,3)10-6(9)8-4-5-11/h11H,4-5H2,1-3H3,(H,8,9) | | InChIKey | GSJJCZSHYJNRPN-UHFFFAOYSA-N | | SMILES | C(OC(C)(C)C)(=O)NCCS |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | F | 10-13-23 | | HS Code | 29309090 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 2-(BOC-AMINO)ETHANETHIOL Usage And Synthesis |
| Chemical Properties | Clear colorless viscous oil | | Uses | 2-(Boc-amino)ethanthiol is used in the synthesis of several organic compounds including a novel, anisamide-targeted cyclodextrin nanoformulation for the delivery of siRNA to prostate cancer cells which is a potential therapeutic option. Also used in the synthesis of bifunctional azobenzene glycoconjugates for cysteine-based photosensitive cross-linking with bioactive peptides. | | reaction suitability | reagent type: cross-linking reagent | | Synthesis | Synthesis of 2-(Boc-amino)ethanethiol: Cysteamine hydrochloride Ra-016 (2.0g, 44mmol) and Boc anhydride (3.5g, 16mmol) were dissolved in dichloromethane (20mL), and triethylamine (2.5mL, 18mmol) was slowly added in an ice-water bath, and the reaction was carried out for 16 hours after the addition and elevated to ambient temperature, and the organic phase was dried and spin-dried to obtain a colorless oil (2.7g, 95%), which was washed with 0.5N HCl and saturated sodium chloride. Wash with 0.5N HCl, saturated sodium chloride, the organic phase was dried and spun dry to obtain colorless oil (2.7g, yield 95%). The colorless oil obtained after NMR analysis was 2-tert-butoxycarbonylaminoethanethiol. |
| | 2-(BOC-AMINO)ETHANETHIOL Preparation Products And Raw materials |
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