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1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol

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1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol manufacturers

  • ID-8
  • ID-8 pictures
  • $56.00
  • 2026-08-04
  • CAS:147591-46-6
  • Purity: 99.77%
  • Supply Ability: 10g
1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol Basic information
Product Name:1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol
Synonyms:1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol;ID 8;1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol ID8;ID 8; ID8;CS-989;1-(4-methoxy-phenyl)-2-methyl-3-nitro-1H-indole-6-ol;ID 8 free base;1H-Indol-6-ol, 1-(4-methoxyphenyl)-2-methyl-3-nitro-
CAS:147591-46-6
MF:C16H14N2O4
MW:298.29
EINECS:
Product Categories:Inhibitors
Mol File:147591-46-6.mol
1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol Structure
1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol Chemical Properties
Melting point 266 °C(dec.)
storage temp. 2-8°C
solubility DMSO: ≥10mg/mL
form powder
color yellow
Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChI1S/C16H14N2O4/c1-10-16(18(20)21)14-8-5-12(19)9-15(14)17(10)11-3-6-13(22-2)7-4-11/h3-9,19H,1-2H3
InChIKeyVVZNWYXIOADGSW-UHFFFAOYSA-N
SMILESCOc1ccc(cc1)-n2c(C)c([N+]([O-])=O)c3ccc(O)cc23
Safety Information
Hazard Codes Xn,N
Risk Statements 22-50
Safety Statements 61
WGK Germany 3
HS Code 2933.99.8290
Storage Class11 - Combustible Solids
MSDS Information
1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol Usage And Synthesis
DescriptionID-8 (147591-46-6) enhances stem cell proliferation and protects pluripotency in culture.1Inhibits Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK).2
UsesID 8 is an indole derivative that sustains embryonic stem cell self-renewal in long-term culture.
General DescriptionID-8 is an inhibitor of dual-specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A).
Biochem/physiol ActionsID-8 sustains self-renewal and pluripotency of mouse embryonic stem cells (ESCs) in vitro. Stimulates proliferation at a steady rate (observed in serum-free media supplemented with 10 μM over a 30 day period).
storage+4°C
References[1] TOMOYUKI MIYABAYASHI. Indole derivatives sustain embryonic stem cell self-renewal in long-term culture.[J]. Bioscience, Biotechnology, and Biochemistry, 2008, 72 5: 1242-1248. DOI:10.1271/bbb.70717
[2] KOUICHI HASEGAWA. Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion.[J]. Stem Cells Translational Medicine, 2012, 1 1: 18-28. DOI:10.5966/sctm.2011-0033
1-(4-Methoxyphenyl)-2-methyl-3-nitro-1H-indol-6-ol Preparation Products And Raw materials
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