3-(3-Trifluoromethyl-phenyl)-propylamine manufacturers
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| | 3-(3-Trifluoromethyl-phenyl)-propylamine Basic information |
| Product Name: | 3-(3-Trifluoromethyl-phenyl)-propylamine | | Synonyms: | RARECHEM AL BW 1078;3-[3-(Trifluoromethyl)phenyl]-1-propanamine;Cinacalcet metabolite M4;Cicalcet metabolite M4;Cinacalcet 3-TFM Amine Impurity;Benzenepropanamine, 3-(trifluoromethyl)-;Cinacalcet Impurity 89;Cinacalcet Impurity 65 | | CAS: | 104774-87-0 | | MF: | C10H12F3N | | MW: | 203.2 | | EINECS: | | | Product Categories: | | | Mol File: | 104774-87-0.mol |  |
| | 3-(3-Trifluoromethyl-phenyl)-propylamine Chemical Properties |
| Boiling point | 222.2±40.0 °C(Predicted) | | density | 1.154±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator, under inert atmosphere | | solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | | form | Oil | | pka | 10.20±0.10(Predicted) | | color | Colourless |
| | 3-(3-Trifluoromethyl-phenyl)-propylamine Usage And Synthesis |
| Uses | Cinacalcet metabolite M4 is a metabolite of Cinacalcet. Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease[1][2]. | | References | [1] Kumar GN, et al. Metabolism and disposition of calcimimetic agent cinacalcet HCl in humans and animalmodels. Drug Metab Dispos. 2004 Dec;32(12):1491-500. DOI:10.1124/dmd.104.000604
[2] Bushinsky DA, et al. Effect of cinacalcet on urine calcium excretion and supersaturation in genetic hypercalciuric stone-forming rats. Kidney Int. 2006 May;69(9):1586-92. DOI:10.1038/sj.ki.5000324 |
| | 3-(3-Trifluoromethyl-phenyl)-propylamine Preparation Products And Raw materials |
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