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1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone

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1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone manufacturers

  • GSK8573
  • GSK8573 pictures
  • $34.00
  • 2026-07-14
  • CAS:1693766-04-9
  • Purity: 99.97%
  • Supply Ability: 10g
1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone Basic information
Product Name:1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone
Synonyms:QBGNWWJANJWNY-UHFFFAOYSA-N;1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone;GSK8573;GSK-8573(negative control of GSK-2801);GSK8573;GSK-8573;GSK 8573;gsk5873;gsk-5873;GSK-5873;GSK5873;GSK 8573
CAS:1693766-04-9
MF:C20H21NO3
MW:323.39
EINECS:
Product Categories:
Mol File:1693766-04-9.mol
1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone Structure
1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone Chemical Properties
density 1.12±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 25 mg/mL (77.31 mM)
form Solid
color Light yellow to yellow
Safety Information
MSDS Information
1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone Usage And Synthesis
UsesGSK8573 is an inactive control compound for GSK2801 (acetyl-lysine competitive inhibitor of BAZ2A and BAZ2B bromodomains). GSK8573 has binding activity to BRD9 with a Kd value of 1.04 μM and is inactive against BAZ2A/B and other bromodomain familiy. GSK8573 can be used as a structurally related negative control compound in biological experiments[1].
IC 50BRD9: 1.04 μM (Kd)
References[1] Chen P, et al. Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B. J Med Chem. 2016 Feb 25;59(4):1410-24. DOI:10.1021/acs.jmedchem.5b00209
1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone Preparation Products And Raw materials
Tag:1-(1-(3-methoxyphenyl)-7-propoxyindolizin-3-yl)ethanone(1693766-04-9) Related Product Information
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