S-Phenylsulfonylcysteine

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S-Phenylsulfonylcysteine Basic information
Product Name:S-Phenylsulfonylcysteine
Synonyms:S-(phenylsulfonyl)-L-cysteine;S-Phenylsulfonylcysteine;L-Cysteine, S-(phenylsulfonyl)-;(2R)-2-Amino-3-(benzenesulfonylsulfanyl)propanoic acid
CAS:97512-83-9
MF:C9H11NO4S2
MW:261.32
EINECS:
Product Categories:
Mol File:97512-83-9.mol
S-Phenylsulfonylcysteine Structure
S-Phenylsulfonylcysteine Chemical Properties
storage temp. Store at -20°C
solubility DMF: 0.1 mg/ml; DMSO: 0.5 mg/ml; PBS (pH 7.2): 0.5 mg/ml
form A crystalline solid
Safety Information
MSDS Information
S-Phenylsulfonylcysteine Usage And Synthesis
DescriptionS-Nitrosylation reactions regulate protein function and mediate nitrosative stress. S-Phenylsulfonylcysteine is a reagent for blocking thiol (-SH) groups on proteins and peptides at room temperature. This is the first step of the thiosulfonate switch technique, in which thiosulfonates are fluorescently tagged with a probe bearing a reactive thiol, such as rhodamine-SH.
UsesS-Phenylsulfonylcysteine is a reagent for blocking thiol (-SH) groups on proteins and peptides[1].
References[1] Reeves BD, et al. Conversion of S-phenylsulfonylcysteine residues to mixed disulfides at pH 4.0: utility in protein thiol blocking and in protein-S-nitrosothiol detection. Org Biomol Chem. 2014 Oct 28;12(40):7942-56. DOI:10.1039/c4ob00995a
S-Phenylsulfonylcysteine Preparation Products And Raw materials
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