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| | NH-(PEG2-acid)2 Basic information |
| Product Name: | NH-(PEG2-acid)2 | | Synonyms: | Acid-apeg4-acid;NH-(PEG2-acid)2;NH-bis(PEG2-acid) HCl salt;NH-bis(PEG2-C2-acid);4,7,13,16-Tetraoxa-10-azanonadecanedioic acid;HN-(PEG2-CH2CH2COOH)2;4,7,13,16-Tetraoxa-10-azanonadecane-1,19-dioic acid;NH-bis(PEG2-acid) | | CAS: | 1919044-99-7 | | MF: | C14H27NO8 | | MW: | 337.37 | | EINECS: | | | Product Categories: | | | Mol File: | 1919044-99-7.mol |  |
| | NH-(PEG2-acid)2 Chemical Properties |
| Boiling point | 521.6±50.0 °C(Predicted) | | density | 1.191±0.06 g/cm3(Predicted) | | pka | 3.97±0.10(Predicted) |
| | NH-(PEG2-acid)2 Usage And Synthesis |
| Description | NH-bis(PEG2-acid) HCl salt is an anqueous soluble branched compound with a central amino group and two terminal carboxylic acids. The amino group is reactive with activated NHs ester, Carboxylic group can react with primary amino groups. | | Uses | NH-bis(PEG2-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | NH-(PEG2-acid)2 Preparation Products And Raw materials |
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