ADRENOMEDULLIN (22-52) (HUMAN) manufacturers
|
| | ADRENOMEDULLIN (22-52) (HUMAN) Basic information |
| Product Name: | ADRENOMEDULLIN (22-52) (HUMAN) | | Synonyms: | ADRENOMEDULLIN FRAGMENT 22-52 HUMAN;ADRENOMEDULLIN (22-52) (HUMAN);ADRENOMEDULLIN (HUMAN, 22-52);H-THR-VAL-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-ASN-VAL-ALA-PRO-ARG-SER-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2;TVQKLAHQIYQFTDKDKDNVAPRSKISPQGY-NH2;THR-VAL-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-ASN-VAL-ALA-PRO-ARG-SER-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2;51: PN: US20050009742 PAGE: 20 claimed sequence;THR-VAL-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-ASN-VAL-ALA-PRO-ARG-SER-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2: TVQKLAHQIYQFTDKDKDNVAPRSKISPQGY-NH2 | | CAS: | 159899-65-7 | | MF: | C159H252N46O48 | | MW: | 3575.98 | | EINECS: | | | Product Categories: | Peptide;Adrenomedullins;Miscellaneous Peptides;Peptides for Cell Biology | | Mol File: | 159899-65-7.mol |  |
| | ADRENOMEDULLIN (22-52) (HUMAN) Chemical Properties |
| density | 1.50±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Soluble in DMSO | | form | Solid | | color | White to off-white | | Sequence | H-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2 |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | ADRENOMEDULLIN (22-52) (HUMAN) Usage And Synthesis |
| Uses | Adrenomedullin (AM) (22-52), human, an NH2 terminal truncated adrenomedullin analogue, is an adrenomedullin receptor antagonist, and also antagonizes the calcitonin generelated peptide (CGRP) receptor in the hindlimb vascular bed of the cat[1][2]. | | Biochem/physiol Actions | Adrenomedullin Fragment 22-52 [ADM22-52] is used as an adrenomedullin (ADM) receptor antagonist to study the functions and mechanism of action of ADM signaling. ADM(22-52) is used to differentiate adrenomedullin binding sites in various cells and tissues. | | References | [1] Champion HC, et al. Adrenomedullin-(22-52) antagonizes vasodilator responses to CGRP but not adrenomedullin in the cat. Am J Physiol. 1997 Jan;272(1 Pt 2):R234-42. DOI:10.1152/ajpregu.1997.272.1.R234
[2] Ziolkowska A, et al. Effects of adrenomedullin and its fragment 22-52 on basal and ACTH-stimulated secretion of cultured rat adrenocortical cells. Int J Mol Med. 2003 May;11(5):613-5. PMID:12684698 |
| | ADRENOMEDULLIN (22-52) (HUMAN) Preparation Products And Raw materials |
|