- 3-AMINO-1,2,4-TRIAZINE
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- $1.10
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2025-11-18
- CAS:1120-99-6
- Min. Order: 1g
- Purity: 99.00%
- Supply Ability: 100 Tons Min
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| | 3-AMINO-1,2,4-TRIAZINE Basic information |
| Product Name: | 3-AMINO-1,2,4-TRIAZINE | | Synonyms: | 3-amino-as-triazin;3-amino-as-triazine;TIMTEC-BB SBB004379;1,2,4-TRIAZIN-3-YLAMINE;3-AMINO-1,2,4-TRIAZINE;3-Amino-1,2,4-triazine,97%;3-Amino-1,2,4-triazine 97%;1,2,4-Triazine-3-ylamine | | CAS: | 1120-99-6 | | MF: | C3H4N4 | | MW: | 96.09 | | EINECS: | 214-324-7 | | Product Categories: | Building Blocks;Heterocyclic Building Blocks;Triazines | | Mol File: | 1120-99-6.mol |  |
| | 3-AMINO-1,2,4-TRIAZINE Chemical Properties |
| Melting point | 174-177 °C(lit.) | | Boiling point | 169.59°C (rough estimate) | | density | 1.2170 (rough estimate) | | refractive index | 1.7380 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | DMSO (Sonicated), Methanol (Slightly, Sonicated) | | pka | 3.67±0.63(Predicted) | | form | Crystalline Powder | | color | Brown | | InChI | InChI=1S/C3H4N4/c4-3-5-1-2-6-7-3/h1-2H,(H2,4,5,7) | | InChIKey | MJIWQHRXSLOUJN-UHFFFAOYSA-N | | SMILES | N1C=CN=C(N)N=1 | | CAS DataBase Reference | 1120-99-6(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39-24/25 | | WGK Germany | 3 | | RTECS | XY2969000 | | HS Code | 29336990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 3-AMINO-1,2,4-TRIAZINE Usage And Synthesis |
| Chemical Properties | BROWN CRYSTALLINE POWDER | | Uses | 1,2,4-Triazin-3-amine can be used as integrade inhibiting antiviral agents. | | Synthesis | Example 22 Synthesis of 1,2,4-triazin-3-amine (16): an aqueous solution of glyoxal (57 kg, 40 wt% aqueous, 393 mol, 0.73 eq.) was slowly added to a suspension of aminoguanidine bicarbonate (73 kg, 536.3 mol) in water (400 L) and the reaction was carried out at room temperature. Immediately after addition, the release of carbon dioxide (CO2) gas was observed. The reaction mixture was stirred continuously at room temperature for 18 hours, and the gas release essentially stopped after about 2 hours. Upon completion of the reaction, the mixture was separated by filtration and the filtrate was evaporated to dryness under reduced pressure. The resulting residue was extracted with cold methanol (MeOH, 3 x 120 L) and the combined methanol extracts were cooled to 0-5 °C to remove insoluble solids. Subsequently, the filtrate was concentrated under reduced pressure and the residue was recrystallized in acetonitrile to give the final 1,2,4-triazin-3-amine (16, 34 kg, theoretical yield 37.76 kg, 90% yield) as fine white needle-like crystals. | | References | [1] Patent: US2009/291956, 2009, A1. Location in patent: Page/Page column 25-26
[2] Chemistry - A European Journal, 2015, vol. 21, # 41, p. 14376 - 14381
[3] Patent: WO2009/29625, 2009, A1. Location in patent: Page/Page column 75 |
| | 3-AMINO-1,2,4-TRIAZINE Preparation Products And Raw materials |
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