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| | (+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Basic information |
| Product Name: | (+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE | | Synonyms: | sk&f77434;(+/-)-SKF-38393, N-ALLYL-, HYDROBROMIDE;(+/-)-SKF-77434 HYDROBROMIDE;SKF 77434 HYDROBROMIDE;(+/-)-N-ALLYL-SKF-38393 HYDROBROMIDE;2,3,4,5-TETRAHYDRO-1-PHENYL-3-(2-PROPENYL)-1H-3-BENZAZEPINE-7,8-DIOL HYDROBROMIDE;(+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE;(+)-SKF-38393, N-ALLYL-, HYDROBROMIDE D1 DOPAMINE AGONIST | | CAS: | 104422-04-0 | | MF: | C19H21NO2 | | MW: | 295.38 | | EINECS: | | | Product Categories: | | | Mol File: | 104422-04-0.mol |  |
| | (+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Chemical Properties |
| Boiling point | 470.406±45.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.157±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | 2-8°C | | solubility | ethanol: 3.2 mg/mL | | form | solid | | pka | 10.186±0.40(predicted) | | color | white or off-white |
| | (+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Usage And Synthesis |
| Uses | N-Allyl-(+/-)-SKF-38393 hydrobromide is a selective dopamine D1-like receptor partial agonist. | | Definition | ChEBI: A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1, an allyl substituent at position 3 and two hydroxy substituents at positions 7 and 8. Selective dopamine D1-like receptor partial agonist (IC50 values are 19
7 and 2425 nM for binding to D1-like and D2-like receptors respectively). Centrally active following systemic administration in vivo. | | Biological Activity | Selective dopamine D 1 -like receptor partial agonist (IC 50 values are 19.7 and 2425 nM for binding to D 1 -like and D 2 -like receptors respectively). Centrally active following systemic administration in vivo . |
| | (+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Preparation Products And Raw materials |
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