4-(2,3,6,7-Tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-benzenesulfonic acid

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4-(2,3,6,7-Tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-benzenesulfonic acid manufacturers

  • PSB 1115
  • PSB 1115 pictures
  • $61.00
  • 2026-07-15
  • CAS:152529-79-8
  • Purity: 98.69%
  • Supply Ability: 10g
4-(2,3,6,7-Tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-benzenesulfonic acid Basic information
Product Name:4-(2,3,6,7-Tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-benzenesulfonic acid
Synonyms:4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonic acid;BENZENESULFONIC ACID,4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-;Benzenesulfonic acid, 4-(2,3,6,9-tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-;4-(2,6-Dioxo-1-propyl-2,3,6,9-tetrahydro-1H-purin-8-yl)benzenesulfonic acid;4-(2,3,6,7-Tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-benzenesulfonic acid
CAS:152529-79-8
MF:C14H14N4O5S
MW:350.35
EINECS:
Product Categories:Adenosine receptor
Mol File:152529-79-8.mol
4-(2,3,6,7-Tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-benzenesulfonic acid Structure
4-(2,3,6,7-Tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-benzenesulfonic acid Chemical Properties
Melting point >300 °C
density 1.522±0.06 g/cm3(Predicted)
storage temp. Store at -20°C, protect from light
solubility Soluble to 100 mM in DMSO and to 20 mM in water with gentle warming
form Powder
pka-1.59±0.50(Predicted)
color Off-white to light brown
Safety Information
MSDS Information
4-(2,3,6,7-Tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-benzenesulfonic acid Usage And Synthesis
UsesPSB-1115 is a selective A2B Adenosine Receptor antagonist. PSB-1115 inhibits the 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced contraction inhibition of acetylcholine (ACh)[1].
DefinitionChEBI: 4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)benzenesulfonic acid is an oxopurine.
in vivo

PSB-1115 (0.5 mg/kg; i.p.; single dose, injected 20 minutes before inhalation) antagonizes the inhibitory effect of the non-selective adenosine receptor agonist NECA (HY-103173) on mucociliary clearance in mice[2].

IC 50A2BR
storageStore at RT
References[1] Michael S, et al. Adenosine A(2A) agonist and A(2B) antagonist mediate an inhibition of inflammation-induced contractile disturbance of a rat gastrointestinal preparation. Purinergic Signal. 2010 Mar;6(1):117-24. DOI:10.1007/s11302-009-9174-y
4-(2,3,6,7-Tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-benzenesulfonic acid Preparation Products And Raw materials
Tag:4-(2,3,6,7-Tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-benzenesulfonic acid(152529-79-8) Related Product Information
2-Phenyl-1H-imidazol-4-amine Benzenesulfonic acid 4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID POTASSIUM SALT PSB 1115 POTASSIUM SALT 4-(2,3,6,7-TETRAHYDRO-2,6-DIOXO-1-PROPYL-1H-PURIN-8-YL)-BENZENESULFONIC ACID 1,3-DIPROPYL-8-P-SULFOPHENYLXANTHINE MONO-P-TOLUENESULFONATE UREA