10,10-Bis[(2-fluoro-4-pyridinyl)methyl]-9(10H)-anthracenone

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10,10-Bis[(2-fluoro-4-pyridinyl)methyl]-9(10H)-anthracenone manufacturers

  • DMP-543
  • DMP-543 pictures
  • $34.00
  • 2026-04-27
  • CAS:160588-45-4
  • Purity: 99.89%
  • Supply Ability: 10g
10,10-Bis[(2-fluoro-4-pyridinyl)methyl]-9(10H)-anthracenone Basic information
Product Name:10,10-Bis[(2-fluoro-4-pyridinyl)methyl]-9(10H)-anthracenone
Synonyms:DMP 543 (XR-543;XR 543;DMP 543;10,10-BIS[(2-FLUORO-4-PYRIDYL)METHYL]ANTHRONE;10,10-Bis((2-fluoropyridin-4-yl)Methyl)anthracen-9(10H)-one;9(10H)-Anthracenone, 10,10-bis[(2-fluoro-4-pyridinyl)methyl]-;DMP 543,DMP543;10,10-bis[(2-fluoropyridin-4-yl)methyl]-9,10-dihydroanthracen-9-one
CAS:160588-45-4
MF:C26H18F2N2O
MW:412.43
EINECS:
Product Categories:Potassium channel
Mol File:160588-45-4.mol
10,10-Bis[(2-fluoro-4-pyridinyl)methyl]-9(10H)-anthracenone Structure
10,10-Bis[(2-fluoro-4-pyridinyl)methyl]-9(10H)-anthracenone Chemical Properties
Melting point 159-161 °C
Boiling point 593.1±50.0 °C(Predicted)
density 1.319±0.06 g/cm3(Predicted)
storage temp. Store at RT
solubility Soluble to 100 mM in DMSO and to 50 mM in ethanol
form Powder
pka0.38±0.10(Predicted)
color White to yellow
Safety Information
MSDS Information
10,10-Bis[(2-fluoro-4-pyridinyl)methyl]-9(10H)-anthracenone Usage And Synthesis
UsesDMP-543 (XR-543) is a KV7 channel blocker, also acts as a potent neurotransmitter release enhancer[1][2].
DefinitionChEBI: 10,10-bis[(2-fluoro-4-pyridinyl)methyl]-9-anthracenone is a member of anthracenes.
References[1] Ipavec V, et al. KV7 channels regulate muscle tone and nonadrenergic noncholinergic relaxation of the rat gastric fundus. Pharmacol Res. 2011 Oct;64(4):397-409. DOI:10.1016/j.phrs.2011.06.016
[2] Zaczek R, et al. Two new potent neurotransmitter release enhancers, 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone and 10,10-bis(2-fluoro-4-pyridinylmethyl)-9(10H)-anthracenone: comparison to linopirdine. J Pharmacol Exp Ther. 1998 May;285(2):724-30. PMID:9580619
10,10-Bis[(2-fluoro-4-pyridinyl)methyl]-9(10H)-anthracenone Preparation Products And Raw materials
Tag:10,10-Bis[(2-fluoro-4-pyridinyl)methyl]-9(10H)-anthracenone(160588-45-4) Related Product Information
5-Fluorouracil 2-Chloro-5-trifluoromethylpyridine DI-2-PYRIDYL KETONE 4-Isopropylpyridine 4-Isobutyl-pyridine Anthrone 4-phenethylpyridine 2-Fluoro-4-methylpyridine 10,10-Dimethylanthrone 4,4'-Trimethylenedipyridine 10,10-BIS[(2-FLUORO-4-PYRIDINYL)METHYL]-9(10H)-ANTHRACENONE