Benzamide, N-[2-methyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-(2-pyridinylmethoxy)-

Request For Quotation
Benzamide, N-[2-methyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-(2-pyridinylmethoxy)- Suppliers list
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Tel: 13816613772
Email: huahero21@sina.com
Company Name: Jinan Jiuli Biotechnology Co. , Ltd.  
Tel: 15865264761
Email: 486064515@qq.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

Benzamide, N-[2-methyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-(2-pyridinylmethoxy)- manufacturers

  • SMO-IN-1
  • SMO-IN-1 pictures
  • $1520.00
  • 2026-04-20
  • CAS:1126365-66-9
  • Purity:
  • Supply Ability: 10g
Benzamide, N-[2-methyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-(2-pyridinylmethoxy)- Basic information
Product Name:Benzamide, N-[2-methyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-(2-pyridinylmethoxy)-
Synonyms:Benzamide, N-[2-methyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-(2-pyridinylmethoxy)-;SMO-IN-1
CAS:1126365-66-9
MF:C24H22N4O2
MW:398.46
EINECS:
Product Categories:
Mol File:1126365-66-9.mol
Benzamide, N-[2-methyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-(2-pyridinylmethoxy)- Structure
Benzamide, N-[2-methyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-(2-pyridinylmethoxy)- Chemical Properties
Boiling point 579.5±50.0 °C(Predicted)
density 1.20±0.1 g/cm3(Predicted)
pka13.32±0.70(Predicted)
Safety Information
MSDS Information
Benzamide, N-[2-methyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-(2-pyridinylmethoxy)- Usage And Synthesis
UsesSMO-IN-1 (Compound 15) is an orally active Smoothened (SMO) inhibitor with an EC50 of 89 nM against sonic Hh protein (shh)[1].
References[1] Yang B, et al. Heteroarylamide smoothened inhibitors: Discovery of N-[2,4-dimethyl-5-(1-methylimidazol-4-yl)phenyl]-4-(2-pyridylmethoxy)benzamide (AZD8542) and N-[5-(1H-imidazol-2-yl)-2,4-dimethyl-phenyl]-4-(2- pyridylmethoxy)benzamide (AZD7254). Bioorg M DOI:10.1016/j.bmc.2019.115227
Benzamide, N-[2-methyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-(2-pyridinylmethoxy)- Preparation Products And Raw materials
Tag:Benzamide, N-[2-methyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-(2-pyridinylmethoxy)-(1126365-66-9) Related Product Information
N-[2,4-dimethyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-[(pyridin-2-yl)methoxy]benzamide Benzamide, N-[5-(1H-imidazol-2-yl)-2-methylphenyl]-4-(2-pyridinylmethoxy)-, hydrochloride (1:2) Hedgehog IN-2 N-[5-(1H-imidazol-2-yl)-2,4-dimethylphenyl]-4-[(pyridin-2-yl)methoxy]benzamide AZ 12080282 Dihydrochloride Benzamide, N-[2-methyl-5-(1-methyl-1H-imidazol-4-yl)phenyl]-4-(2-pyridinylmethoxy)-