| Company Name: |
HBCChem, Inc. |
| Tel: |
+1-510-219-6317 |
| Email: |
sales@hbcchem.com |
|
| | 2-Hydrazino-4,6-dimethylpyrimidine Basic information |
| Product Name: | 2-Hydrazino-4,6-dimethylpyrimidine | | Synonyms: | 2(1H)-Pyrimidinone, 4,6-dimethyl-, hydrazone (7CI,9CI);4,6-Dimethyl-2-hydrazinopyrimidine;2-Hydrazino-4,6-dimethylpyrimidine;2-hydrazino-4,6-dimethylpyrimidine(SALTDATA: FREE);2-Hydrazino-4;2(1H)-Pyrimidinone, 4,6-dimethyl-, hydrazone;2-hydrazineyl-4,6-dimethylpyrimidine;2-Hydrazino-4,6-dimethylpyrimidine Solution | | CAS: | 23906-13-0 | | MF: | C6H10N4 | | MW: | 138.17 | | EINECS: | | | Product Categories: | PYRIMIDINE | | Mol File: | 23906-13-0.mol |  |
| | 2-Hydrazino-4,6-dimethylpyrimidine Chemical Properties |
| Melting point | 165 °C | | Boiling point | 256.0±23.0 °C(Predicted) | | density | 1.26±0.1 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | pka | 6.44±0.70(Predicted) | | color | White to Off-White |
| | 2-Hydrazino-4,6-dimethylpyrimidine Usage And Synthesis |
| Synthesis | General procedure for the synthesis of 2-hydrazino-4,6-dimethylpyrimidines using 2-chloro-4,6-dimethylpyrimidines as starting material: hydrazine monohydrate (1.02 mL, 21.0 mmol) was slowly added to a solution of ethanol (5 mL) containing 2-chloro-4,6-dimethylpyrimidines (2 g, 14.0 mmol). The reaction mixture was stirred continuously for 2 hours at room temperature. Upon completion of the reaction, the precipitate precipitated was collected by vacuum filtration and washed with cold methanol. The resulting solid was dried under a stream of air to give 2-hydrazino-4,6-dimethylpyrimidine (1 g, 52% yield) as a white solid. The product was confirmed by mass spectrometry (ESI+) with a m/z of 139 (MH+). | | References | [1] Patent: WO2012/154880, 2012, A1. Location in patent: Page/Page column 60
[2] Journal of the Chemical Society, 1952, p. 4691,4694
[3] Farmaco, Edizione Scientifica, 1956, vol. 11, p. 389,393
[4] Farmaco, Edizione Scientifica, 1983, vol. 38, # 4, p. 255 - 264
[5] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1989, vol. 25, # 12, p. 1369 - 1373 |
| | 2-Hydrazino-4,6-dimethylpyrimidine Preparation Products And Raw materials |
|