- 5-Hydroxyindole
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- $1.10 / 1g
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2025-11-18
- CAS:1953-54-4
- Min. Order: 1g
- Purity: 99.0% Min
- Supply Ability: 100 Tons
- 5-Hydroxyindole
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- $8.00 / 1kg
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2025-09-25
- CAS:1953-54-4
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- 5-Hydroxyindole
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- $30.00 / 1KG
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2025-06-27
- CAS:1953-54-4
- Min. Order: 50KG
- Purity: 99%
- Supply Ability: 500000kg
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| | 5-Hydroxyindole Basic information |
| | 5-Hydroxyindole Chemical Properties |
| Melting point | 106-108 °C(lit.) | | Boiling point | 245.66°C (rough estimate) | | density | 1.1475 (rough estimate) | | refractive index | 1.5260 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C | | solubility | 38g/l | | pka | 9.98±0.40(Predicted) | | form | Crystalline Needles or Powder | | color | beige | | Sensitive | Light Sensitive | | BRN | 112349 | | InChI | InChI=1S/C8H7NO/c10-7-1-2-8-6(5-7)3-4-9-8/h1-5,9-10H | | InChIKey | LMIQERWZRIFWNZ-UHFFFAOYSA-N | | SMILES | N1C2=C(C=C(O)C=C2)C=C1 | | CAS DataBase Reference | 1953-54-4(CAS DataBase Reference) | | NIST Chemistry Reference | Indol-5-ol(1953-54-4) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36-37/39 | | WGK Germany | 3 | | RTECS | NM2430000 | | HazardClass | IRRITANT, KEEP COLD | | HS Code | 29339990 | | Storage Class | 11 - Combustible Solids |
| | 5-Hydroxyindole Usage And Synthesis |
| Chemical Properties | beige to brown crystalline needles or powder | | Uses | • ;Reactant for preparation of (oxoimidazolidinyl/oxopyrimidinyl)benzenesulfonates as antitumor agents and tubulin inhibitors1• ;Reactant for preparation of anthranilic acids2• ;Reactant for preparation of indole compounds as dopamine D2 receptor antagonists3• ;Reactant for preparation of naphthalimide- or carbazole-containing human β-adrenoceptor ligands4• ;Reactant for preparation of melanins as nature-inspired radioprotectors5• ;Reactant for preparation of 5-vinyl-3-pyridinecarbonitriles as PKCθ inhibitors6 | | Uses | 5-Hydroxyindole is a hydroxylated indole used as a building block in the preparation of various pharmaceutical compounds such as indole based neurochemicals. 5-Hydroxyindole is a metabolite of Tryptophan (T894800). 5-Hydroxyindole displayed weak inhibitory activity on human melanoma tyrosinase. 5-Hydroxyindole also showed inhibition of serotonin transport by blood platelets. | | Definition | ChEBI: 5-hydroxyindole is a member of the class of hydroxyindoles that is 1H-indole in which the hydrogen at position 5 has been replaced by a hydroxy group. It has a role as a human metabolite. | | Synthesis Reference(s) | Journal of the American Chemical Society, 76, p. 5579, 1954 DOI: 10.1021/ja01651a001
The Journal of Organic Chemistry, 49, p. 4833, 1984 DOI: 10.1021/jo00199a017 |
| | 5-Hydroxyindole Preparation Products And Raw materials |
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