Trifluoroacetaldehyde ethyl hemiacetal

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Trifluoroacetaldehyde ethyl hemiacetal manufacturers

Trifluoroacetaldehyde ethyl hemiacetal Basic information
Product Name:Trifluoroacetaldehyde ethyl hemiacetal
Synonyms:1-ethoxy-2,2,2-trifluoro-ethano;(contains ca. 10% Ethanol);Trifluoroacetaldehyde Ethyl HeMiacetal ;1-Ethoxy-2,2,2-trifluoroethan-1-ol, 2-Ethoxy-2-hydroxy-1,1,1-trifluoroethane;Trifluoroacetaldehyde ethyl hemiacetal 90%;Trifluoroacetaldehyde Ethyl Hemiacetal (contains ca. 10% Ethanol);TFAL-ETOH;TRIFLUOROACETALDEHYDE HEMIETHYLACETAL
CAS:433-27-2
MF:C4H7F3O2
MW:144.09
EINECS:207-087-6
Product Categories:Acetals/Ketals/Ortho Esters;Building Blocks;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Fluorinated Building Blocks;Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds;Synthetic Organic Chemistry
Mol File:433-27-2.mol
Trifluoroacetaldehyde ethyl hemiacetal Structure
Trifluoroacetaldehyde ethyl hemiacetal Chemical Properties
Boiling point 104-105 °C/745 mmHg (lit.)
density 1.221 g/mL at 25 °C (lit.)
refractive index n20/D 1.342(lit.)
Fp 97 °F
storage temp. 2-8°C
solubility Chloroform, Ethyl Acetate
pka10.57±0.20(Predicted)
form Liquid
Specific Gravity1.241
color Clear colorless
BRN 906797
InChI1S/C4H7F3O2/c1-2-9-3(8)4(5,6)7/h3,8H,2H2,1H3
InChIKeyKLXJPQNHFFMLIG-UHFFFAOYSA-N
SMILES[Na+].[O-]c1ccccc1
CAS DataBase Reference433-27-2(CAS DataBase Reference)
NIST Chemistry ReferenceEthanol, 1-ethoxy-2,2,2-trifluoro-(433-27-2)
EPA Substance Registry SystemEthanol, 1-ethoxy-2,2,2-trifluoro- (433-27-2)
Safety Information
Hazard Codes Xn,T,F
Risk Statements 10-22-11-2017/10/22
Safety Statements 16-24-23-45-36/37/39
RIDADR UN 1993 3/PG 3
WGK Germany 3
RTECS KK9000000
Hazard Note Toxic/Flammable
TSCA TSCA listed
HazardClass 3
PackingGroup III
HS Code 29110000
Storage Class3 - Flammable liquids
Hazard ClassificationsEye Irrit. 2
Flam. Liq. 3
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
Trifluoroacetaldehyde ethyl hemiacetal Usage And Synthesis
Chemical Propertiesclear colorless liquid
UsesAlternative to gaseous unstable trifluoroacetaldehyde: used to prepare α-trifluoromethylated alcohols for antifungals, antitumor, and chemotherapeutic agents.1,2,3
UsesTrifluoroacetaldehyde Ethyl Hemiacetal is used in the synthesis of peptidomimetic inhibitors of the human cytomegalovirus protease. It is also used in the synthesis of transforming growth factor-β type receptor inhibitors.
Tag:Trifluoroacetaldehyde ethyl hemiacetal(433-27-2) Related Product Information
Trifluoroacetaldehyde hydrate Neodymium(III) trifluoromethanesulfonate Gallium(III) trifluoromethanesulfonate O-(2,2,2-Trifluoroethyl)hydroxylamine hydrochloride 2,2,2-Trifluoro-1,1-diethoxyethane Lithium trifluoromethanesulfonate Trifluoromethanesulfonic acid difluoromethyl ester Nickel(II) Trifluoromethanesulfonate Sodium trifluoroacetate Potassium trifluoroacetate Potassium trifluoromethanesulfonate Methyl trifluoroacetate Praseodymium (III) trifluoromethanesulfonate Phenyl trifluoroacetate Trifluoroacetaldehyde methyl hemiacetal Trifluoroacetaldehyde dimethyl acetal Magnesium trifluoromethanesulfonate Erbium (III) trifluoromethanesulfonate