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| | Termitomycamide E Basic information |
| Product Name: | Termitomycamide E | | Synonyms: | Termitomycamide E;(9Z,12Z)-N-[2-(4-hydroxyphenyl)ethyl]octadeca-9,12-dienamide;9,12-Octadecadienamide, N-[2-(4-hydroxyphenyl)ethyl]-, (9Z,12Z)- | | CAS: | 1177258-62-6 | | MF: | C26H41NO2 | | MW: | 399.61 | | EINECS: | | | Product Categories: | | | Mol File: | 1177258-62-6.mol |  |
| | Termitomycamide E Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH7.2)(1:20): 0.05 mg/ml | | form | A crystalline solid |
| | Termitomycamide E Usage And Synthesis |
| Description | Endoplasmic reticulum (ER) stress, caused by accumulation of misfolded proteins and a disruption of calcium homeostasis, has been linked to several neuronal diseases including, Parkinson’s, Alzheimer’s, and prion diseases. A screen for protective activity against ER stress-dependent cell death identified termitomycamides, extracts from the fruiting bodies of T. titanicus, a notably large edible mushroom that is cultivated symbiotically in the nests of termites. Termitomycamide E is a fatty acid isolated from T. titanicus that at a dose of 0.1 μg/ml protects against ER stress-dependent cell death in Neuro2a cells induced by tunicamycin.1 | | Uses | Termitomycamide E is a fatty acid amide that can suppress endoplasmic reticulum stress. Termitomycamide E shows significant protective activity against T. titanicus-toxicity[1]. | | References | 1. Choi, J.H., Maeda, K., Nagai, K., et al. Termitomycamides A to E, fatty acid amides isolated from the mushroom Termitomyces titanicus, suppress endoplasmic reticulum stress Org. Lett. 12(21),5012-5015(2010). |
| | Termitomycamide E Preparation Products And Raw materials |
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