4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(2-fluorophenyl)-1-butanone

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4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(2-fluorophenyl)-1-butanone Basic information
Product Name:4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(2-fluorophenyl)-1-butanone
Synonyms:4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(2-fluorophenyl)-1-butanone;4-Defluoro-2-fluoro Haloperidol;4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-1-(2-fluorophenyl)butan-1-one;Haloperidol Impurity 2(Haloperidol EP Impurity B);Haloperidol EP Impurity B;1-Butanone, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(2-fluorophenyl)-;Haloperidol EP impuritiesB;4-(4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl)-1-(2-fluorophenyl)butan-1-one (Haloperidol Impurity)
CAS:1391052-53-1
MF:C21H23ClFNO2
MW:375.86
EINECS:
Product Categories:Aromatics, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Aromatics;Heterocycles;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:1391052-53-1.mol
4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(2-fluorophenyl)-1-butanone Structure
4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(2-fluorophenyl)-1-butanone Chemical Properties
Melting point 106 - 108°C
Boiling point 529.0±50.0 °C(Predicted)
density 1.239±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka13.86±0.20(Predicted)
color White to Off-White
Major Applicationpharmaceutical
InChI1S/C21H23ClFNO2/c22-17-9-7-16(8-10-17)21(26)11-14-24(15-12-21)13-3-6-20(25)18-4-1-2-5-19(18)23/h1-2,4-5,7-10,26H,3,6,11-15H2
InChIKeyURVMQMKGIVIILI-UHFFFAOYSA-N
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
MSDS Information
4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(2-fluorophenyl)-1-butanone Usage And Synthesis
Uses4-Defluoro-2-fluoro Haloperidol is a positional isomer and impurity of the antipsychotic agent Haloperidol (H103700).
4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(2-fluorophenyl)-1-butanone Preparation Products And Raw materials
Tag:4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(2-fluorophenyl)-1-butanone(1391052-53-1) Related Product Information
Dechloro Haloperidol (Haloperidol Impurity B) 4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(3-ethyl-4-fluorophenyl)-1-butanone Haloperidol EP Impurity E Haloperidol Haloperidol EP Impurity F 2-Chloro-4'-fluoroacetophenone 4-Fluorobenzoyl chloride Haloperidol N-Oxide Cyclopropyl 4-fluorophenyl ketone 4-Chloro-4'-fluorobutyrophenone 5-Chloro-1-(4-fluorophenyl)-1-oxopentane 3-Chloro-4'-fluoropropiophenone Haloperidol related compound A (15 mg) (4,4'-bis[(4-p-chlorophenyl)-4-hydroxy-piperidino]-Bu-tyrophenone) 4-Chloro-1-(2-fluorophenyl)-1-oxobutane 1-(4-Fluorophenyl)-4-hydroxybutan-1-one 6-Chloro-1-(4-fluorophenyl)-1-oxohexane 4-Chloro-1-(3-fluorophenyl)-1-oxobutane N-(4'-fluorobutyrophenone)-4-(4-chlorophenyl)pyridinium