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2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide

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2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
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Products Intro: Product Name:HydroxyDynasore
CAS:1256493-34-1
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
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Products Intro: Product Name: 2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide
CAS:1256493-34-1
Purity:99.99% Package:1g;1USD
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Products Intro: Product Name:Hydroxy-Dynasore
CAS:1256493-34-1
Purity:>=95% Package:5mg;46USD|10mg;76USD|25mg;139USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
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Products Intro: Product Name:Dyngo-4a
CAS:1256493-34-1
Purity:61999% Package:10kg 25kg 200 kilograms per barrel Remarks:good
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Products Intro: Product Name:Hydroxy-Dynasore
CAS:1256493-34-1
Purity:98% Package:1g,10g,25g,100g,500g,1kg Remarks:N/A

2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide manufacturers

  • Hydroxy-Dynasore
  • Hydroxy-Dynasore pictures
  • $46.00
  • 2026-07-17
  • CAS:1256493-34-1
  • Purity: 97.60%
  • Supply Ability: 10g
2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide Basic information
Product Name:2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide
Synonyms:2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide;Dyngo-49;3-Hydroxy-2-naphthalenecarboxylic acid 2-[(2,4,5-trihydroxyphenyl)methylene]hydrazide;3-Hydroxy-N′-[(2,4,5-trihydroxyphenyl)methylidene]naphthalene-2-carbohydrazide;Hydroxy-Dynasore;3-Hydroxynaphthalene-2-carboxylic acid 2-[(2,4,5)-trihydroxyphenyl)methylene]hydrazide;Dyng;o-4a
CAS:1256493-34-1
MF:C18H14N2O5
MW:338.31
EINECS:
Product Categories:
Mol File:1256493-34-1.mol
2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide Structure
2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide Chemical Properties
density 1.45±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: >10mg/mL
pka8.28±0.40(Predicted)
form powder
color faint yellow to dark yellow
InChI1S/C18H14N2O5/c21-14-8-17(24)16(23)7-12(14)9-19-20-18(25)13-5-10-3-1-2-4-11(10)6-15(13)22/h1-9,21-24H,(H,20,25)/b19-9+
InChIKeyUAXHPUSKEWEOAP-DJKKODMXSA-N
SMILESOc1cc(O)c(\C=N\NC(=O)c2cc3ccccc3cc2O)cc1O
Safety Information
Hazard Codes N
Risk Statements 50
Safety Statements 61
WGK Germany 3
Storage Class11 - Combustible Solids
MSDS Information
2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide Usage And Synthesis
UsesHydroxy-Dynasore is an inhibitor of dynamin I and dynamin II.
DefinitionChEBI: Dyngo-4a is dynamin inhibitor. It has a role as an EC 3.6.5.5 (dynamin GTPase) inhibitor.
Biochem/physiol ActionsHydroxy-Dynasore is a cell permeable and potent dynamin inhibitor that prevents uptake of recombinant botulinum neurotoxin A heavy chain binding domain (BoNT/A-Hc). Apparently, Hydroxy-Dynasore prevents dynamin-mediated fission of endocytic vesicles from the plasma membrane.
in vivo

Hydroxy Dynasore (intraperitoneal injection; 30 mg/kg; 1.5-2 h before BoNT/A injection) provides protection again BoNT/A-induced paralysis in the phrenic nerve-hemidiaphragm twitch model in CD-1 mice[2].

Animal Model:CD-1 mice[2].
Dosage:30 mg/kg
Administration:Intraperitoneal injection; 1.5–2 h before BoNT/A injection
Result:Protected BoNT/A-induced paralysis in vivo.
storageStore at -20°C
2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide Preparation Products And Raw materials
Tag:2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[(2,4,5-trihydroxyphenyl)Methylene]hydrazide(1256493-34-1) Related Product Information
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