Hydroxy-Dynasore NEW
| Price | $46 | $76 | $139 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-04 |
Product Details
| Product Name: Hydroxy-Dynasore | CAS No.: 1256493-34-1 |
| Purity: 97.60% | Supply Ability: 10g |
| Release date: 2025/11/04 |
Product Introduction
Bioactivity
| Name | Hydroxy-Dynasore |
| Description | Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM, respectively. |
| In vitro | Dyngo-4a inhibits dynamin-dependent endocytosis of transferrin in multiple cell types with IC?? of 5.7 μM, and reduces synaptic vesicle endocytosis and activity-dependent bulk endocytosis in cultured neurons and synaptosomes. [1] In motor nerve terminals and cultured hippocampal neurons, Dyngo-4a blocks Alexa Fluor 488-BoNT/A-Hc internalization. [2] In Drosophila S2R+ cells, Dyngo-4a causes a decrease in the level of Armadillo/β-catenin. [3] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 45 mg/mL (133.01 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (5.91 mM), Sonication is recommended. |
| Keywords | vesicle | Neuron | Inhibitor | inhibit | Hydroxy-Dynasore | HydroxyDynasore | Hydroxy Dynasore | Endocytosis,Dynamin,GTPase | DynII (rec) | DynI (rec) | DynI (brain) | Dynamin | clathrin‐coated |
| Inhibitors Related | IIQLPEIVVV TFA | Trimethyloctadecylammonium bromide | POSH-IN-2 | Dynamin inhibitory peptide, myristoylated acetate | Mdivi-1 | Dynamin IN-2 | Dynasore | Dynapyrazole A | Schaftoside | Tetradecyltrimethylammonium bromide |
| Related Compound Libraries | Bioactive Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Cytoskeletal Signaling Pathway Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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