Ald-PEG3-Azide

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Ald-PEG3-Azide Basic information
Product Name:Ald-PEG3-Azide
Synonyms:Ald-PEG3-Azide;ALD-CH2-PEG3-AZIDE;Ald-CH2-PEG3-N3;CHO-PEG3-azide;N3-PEG3-CH2CHO
CAS:1002342-83-7
MF:C8H15N3O4
MW:217.23
EINECS:
Product Categories:peg
Mol File:1002342-83-7.mol
Ald-PEG3-Azide Structure
Ald-PEG3-Azide Chemical Properties
solubility Soluble in Water, DMSO, DMF, DCM
Safety Information
MSDS Information
Ald-PEG3-Azide Usage And Synthesis
DescriptionAld-CH2-PEG3-azide is a click chemistry PEG linker. Aldehyde groups are likely to undergo nucleophile substitution, reduction and oxidation reactions. The azideN3 enable Click Chemistry reactions with alkynes, DBCO and BCN to form triazole groups. PEG3 spacer increases the water solubility of the compound.
Biological ActivityAld-CH2-PEG3-azide is a cleavable 3-unit PEG-containing ADC linker that can be used to synthesize antibody drug conjugates (ADCs),it is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

Cleavable

PEGs

Ald-PEG3-Azide Preparation Products And Raw materials
Raw materials1-Azido-3,6,9-trioxaundecane-11-ol
Tag:Ald-PEG3-Azide(1002342-83-7) Related Product Information
Ald-PEG5-t-butyl ester Acid-PEG5-t-butyl ester Ald-Ph-PEG2-amine m-PEG4-benzaldehyde Ald--Ph-PEG2-NHS Ald-PEG4-NHS ester Ald-Ph-PEG6-t-butyl ester Ald-Ph-PEG3-Azide m-PEG4-CH2-aldehyde Ald-PEG5-Azide Azido-PEG3-aldehyde Azide-PEG3-Desthiobiotin Azido-PEG16-t-butyl ester Ald-Ph-PEG4-t-butyl ester Ald--Ph-PEG3-amine Ald--Ph-PEG6-acid Ald-Ph-PEG2-NHBoc CHO-PEG8-azide

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