Ald--Ph-PEG3-amine manufacturers
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| | Ald--Ph-PEG3-amine Basic information |
| Product Name: | Ald--Ph-PEG3-amine | | Synonyms: | CHO-Ph-PEG3-amine TFA;Ald--Ph-PEG3-amine;ALD-PH-NH-PEG3-NH2;DF-PEG3-NH2;Ald-Ph-PEG3-amine TFA salt;Ald-Ph-amido-PEG3-C2-NH2;CHO-Ph-CONH-PEG3-amine TFA;Benzamide, N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-4-formyl- | | CAS: | 1404111-56-3 | | MF: | C16H24N2O5 | | MW: | 324.37 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1404111-56-3.mol |  |
| | Ald--Ph-PEG3-amine Chemical Properties |
| Boiling point | 542.8±50.0 °C(Predicted) | | density | 1.159±0.06 g/cm3(Predicted) | | pka | 13.53±0.46(Predicted) |
| | Ald--Ph-PEG3-amine Usage And Synthesis |
| Description | Ald-Ph-PEG3-amine TFA salt is a PEG linker containing a benzaldehyde group which is able to undergo reactions with primary amines. The terminal primary amine can react with carboxylic acids, activated NHS ester groups and other carbonyl compounds. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous environments. | | Uses | Ald-Ph-amido-PEG3-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005 |
| | Ald--Ph-PEG3-amine Preparation Products And Raw materials |
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