Ald-Ph-PEG2-amine manufacturers
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| | Ald-Ph-PEG2-amine Basic information |
| Product Name: | Ald-Ph-PEG2-amine | | Synonyms: | Ald-Ph-PEG2-amine;Ald-Ph-PEG2-amine TFA salt;CHO-Ph-PEG2-amine TFA;Ald-Ph-amido-C2-PEG2-amine;Benzamide, N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-4-formyl-;CHO-Ph-CONH-PEG2-amine TFA;CHO-Ph-CONH-PEG2-amine | | CAS: | 2055013-56-2 | | MF: | C14H20N2O4 | | MW: | 280.32 | | EINECS: | | | Product Categories: | peg | | Mol File: | 2055013-56-2.mol |  |
| | Ald-Ph-PEG2-amine Chemical Properties |
| Boiling point | 507.8±45.0 °C(Predicted) | | density | 1.166±0.06 g/cm3(Predicted) | | pka | 13.53±0.46(Predicted) |
| | Ald-Ph-PEG2-amine Usage And Synthesis |
| Description | Ald-Ph-PEG2-amine TFA salt is a small molecule PEG linker with a benzaldehyde moiety and a terminal amine NH2 group. The benzaldehyde can undergo reactions with primary amine groups. The primary amine can react with carboxylic acids, activated NHS esters and other carbonyl compounds. The hydrophilic PEG linkers increase the water solubility of the compound in aqueous solutions. | | Uses | Ald-Ph-amido-C2-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Ald-Ph-PEG2-amine Preparation Products And Raw materials |
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