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UNC3866

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Company Name: ATK CHEMICAL COMPANY LIMITED
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Products Intro: Product Name:UNC3866
CAS:1872382-47-2
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
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Products Intro: Product Name:UNC3866
CAS: 1872382-47-2
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Products Intro: Product Name:UNC3866
CAS:1872382-47-2
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Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
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Products Intro: Product Name:UNC3866
CAS:1872382-47-2
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Company Name: Zhejiang J&C Biological Technology Co.,Limited
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Products Intro: Product Name:UNC3866
CAS:1872382-47-2
Purity:99% Package:5KG;1KG Remarks:UNC3866

UNC3866 manufacturers

  • UNC3866
  • UNC3866 pictures
  • $48.00 / 1mg
  • 2026-04-20
  • CAS:1872382-47-2
  • Min. Order:
  • Purity: 99.62%
  • Supply Ability: 10g
  • UNC3866
  • UNC3866 pictures
  • $7.00 / 1KG
  • 2020-02-14
  • CAS: 1872382-47-2
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 100KG
UNC3866 Basic information
Product Name:UNC3866
Synonyms:UNC3866;N-[4-(1,1-Dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-L-serine methyl ester;CS-2491;UNC 3866;UNC-3866;(3S,6S,9S,12S,15S)-Methyl 3-benzyl-1-(4-(tert-butyl)phenyl)-12-(4-(diethylamino)butyl)-15-(hydroxymethyl)-9-isobutyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecan-16-oate;L-Serine, N-[4-(1,1-dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-, methyl ester;UNC3866,inhibit,Histone Methyltransferase,UNC-3866,Inhibitor,UNC 3866;UNC3866, 10 mM in DMSO
CAS:1872382-47-2
MF:C43H66N6O8
MW:795.02
EINECS:
Product Categories:
Mol File:1872382-47-2.mol
UNC3866 Structure
UNC3866 Chemical Properties
Boiling point 1034.5±65.0 °C(Predicted)
density 1.129±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility Soluble in DMSO
form A crystalline solid
pka13.39±0.46(Predicted)
color White to off-white
Safety Information
MSDS Information
UNC3866 Usage And Synthesis
DescriptionUNC3866 is an inhibitor of chromobox homolog 7 (CBX7; Kd = 97 nM). It also binds to CBX4 (Kd = 94 nM) but is greater than 6-fold selective over CBX2, 6, and 8 and the chromodomain Y family (CDY) chromodomains CDY1, L1b, and L2 (Kds = 0.61-6.3 μM). UNC3866 pretreatment (30 μM) of PC3 lysates completely inhibits chemiprecipitation of CBX7. It induces a senescent-like morphology and reduces growth of PC3 cells with an EC50 value of 7.6 μM.
UsesPolycomb group proteins (CBX4, CBX7) regulate cell fate decisions during embryogenesis. N-[4-(1,1-Dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-L-serine Methyl Ester is a selective antagonist of CBX4 and CBX7 chromodomains. It also inhibits prostate cell proliferation.
UNC3866 Preparation Products And Raw materials
Tag:UNC3866(1872382-47-2) Related Product Information
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