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| | (R)-(+)-2-AMINO-3-METHYL-1,1-DIPHENYL-1-BUTANOL Basic information | | Application |
| Product Name: | (R)-(+)-2-AMINO-3-METHYL-1,1-DIPHENYL-1-BUTANOL | | Synonyms: | 2-AMINO-3-METHYL-1,1-DIPHENYLBUTAN-1-OL;(R)-(+)-2-Amino-3-methyl-1,1-diphenyl-1-butanol;R-2-amino-3-methyl-1,1-diphenylbutan-1-ol;(R)-(+)-2-Amino-3-methyl-1,1-diphenyl-1-butanol;(R)-2-Amino-3-methyl-1,1-diphenyl-1-butanol,99%e.e.;(R)-(+)-2-Amino-3-methyl-1,1-diphenyl-1-butanol >;Benzenemethanol, α-[(1R)-1-amino-2-methylpropyl]-α-phenyl-;-1,1-diphenyL | | CAS: | 86695-06-9 | | MF: | C17H21NO | | MW: | 255.36 | | EINECS: | | | Product Categories: | Amino Alcohols;Chiral Building Blocks;Organic Building Blocks;Chiral Reagents | | Mol File: | 86695-06-9.mol |  |
| | (R)-(+)-2-AMINO-3-METHYL-1,1-DIPHENYL-1-BUTANOL Chemical Properties |
| Melting point | 95-99 °C(lit.) | | Boiling point | 424.7±40.0 °C(Predicted) | | density | 1.074±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | form | powder to crystal | | pka | 11.20±0.50(Predicted) | | color | White to Almost white | | Optical Rotation | [α]20/D +132°, c = 1 in chloroform |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HS Code | 29062990 |
| | (R)-(+)-2-AMINO-3-METHYL-1,1-DIPHENYL-1-BUTANOL Usage And Synthesis |
| Application | (R)-(+)-2-amino-3-methyl-1,1-diphenyl-1-butanol can be used as a pharmaceutical synthesis intermediate. It can be prepared from (D)-valine as a reactant or from Boc-D-valine methyl ester. It is mainly used in laboratory research and development and chemical production processes. | | Chemical Properties | White powder | | Synthesis | 1. D-Valine reacts with SOCl/MeOH to give D-valine methyl ester.
2. D-Valine methyl ester reacts with a Grignard reagent prepared from bromobenzene to yield (R)-(+)-2-amino-3-methyl-1,1-diphenyl-1-butanol. |
| | (R)-(+)-2-AMINO-3-METHYL-1,1-DIPHENYL-1-BUTANOL Preparation Products And Raw materials |
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