- Tosyl cyanide
-
-
2026-09-11
- CAS:19158-51-1
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 30tons/month
- Tosyl cyanide
-
- $100.00
-
2026-09-02
- CAS:19158-51-1
- Min. Order: 1KG
- Purity: 99%
- Tosyl cyanide
-
- $70.00
-
2026-08-25
- CAS:19158-51-1
- Min. Order: 10kg
- Purity: 0.99
- Supply Ability: 20tons
|
| | Tosyl cyanide Basic information |
| | Tosyl cyanide Chemical Properties |
| Melting point | 47-50 °C (lit.) | | Boiling point | 105-106 °C/1 mmHg (lit.) | | density | 1.3055 (rough estimate) | | refractive index | 1.5650 (estimate) | | Fp | >230 °F | | storage temp. | 2-8°C | | solubility | Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Sparingly), Ethyl Acetate | | form | crystalline solid | | color | White | | BRN | 2048159 | | Stability: | Hygroscopic, Moisture Sensitive | | InChI | InChI=1S/C8H7NO2S/c1-7-2-4-8(5-3-7)12(10,11)6-9/h2-5H,1H3 | | InChIKey | JONIMGVUGJVFQD-UHFFFAOYSA-N | | SMILES | C1(S(C#N)(=O)=O)=CC=C(C)C=C1 | | CAS DataBase Reference | 19158-51-1(CAS DataBase Reference) |
| Hazard Codes | C | | Risk Statements | 20/21-34 | | Safety Statements | 26-27-28-36/37/39-45 | | RIDADR | UN 3261 8/PG 2 | | WGK Germany | 3 | | F | 10-21 | | HazardClass | 8 | | PackingGroup | III | | HS Code | 2930909899 | | Storage Class | 8A - Combustible corrosive hazardous materials | | Hazard Classifications | Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Eye Dam. 1
Skin Corr. 1B |
| | Tosyl cyanide Usage And Synthesis |
| Chemical Properties | White powder | | Uses | p-Toluenesulfonyl cyanide can be used in:
- The preparation of polyfunctional nitriles.
- Free-radical cyanation of B-alkylcatecholboranes.
- The synthesis of 4-hyroxypyridines by hetero-Diels-Alder reaction with 1,3-bis-silyl enol ethers.
| | Uses | Tosyl cyanide is used in a free-radical cyanation of B-alkylcatecholboranes. Also used as a component in a hetero-Diels-Alder reaction with 1,3-bis-silyl enol ethers leading to 4-hyroxypyridines. | | Synthesis Reference(s) | Tetrahedron Letters, 10, p. 3351, 1969 DOI: 10.1017/S0009838800024678 | | General Description | p-Toluenesulfonyl cyanide is an electron-deficient nitrile. It undergoes hetero-Diels-Alder reaction with silyl enol ether of cyclohexenone to yield hydrolytically sensitive [4+2] adduct. It also undergoes facile [2+3] cycloaddition reaction with azides to form 5-sulfonyl tetrazoles. p-Toluenesulfonyl cyanide also reacts with alcohols in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) or 1,4-diazabicyclo[2.2.2]octane (DABCO) to yield sulfinates. |
| | Tosyl cyanide Preparation Products And Raw materials |
|