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| | 6-FLUOROQUINAZOLIN-4-ONE Basic information |
| Product Name: | 6-FLUOROQUINAZOLIN-4-ONE | | Synonyms: | 6-FLUOROQUINAZOLIN-4-ONE;6-Fluoroquinazolin-4-ol;6-Fluoro-3H-quinazolin-4-one;6-fluoro-1H-quinazolin-4-one;4(3H)-Quinazolinone, 6-fluoro-;6-Fluoroquinazolin-4(3H)-one, 95+%;6-fluoroquinazolin-4(3H)-one;6-Fluoro-4-hydroxyquinazoline | | CAS: | 16499-56-2 | | MF: | C8H5FN2O | | MW: | 164.14 | | EINECS: | | | Product Categories: | pharmacetical | | Mol File: | 16499-56-2.mol |  |
| | 6-FLUOROQUINAZOLIN-4-ONE Chemical Properties |
| Melting point | 250 °C | | Boiling point | 318.3±44.0 °C(Predicted) | | density | 1.44±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | pka | 1.28±0.20(Predicted) | | Appearance | Off-white to light yellow Solid |
| Hazard Codes | Xn | | Risk Statements | 22 | | HazardClass | IRRITANT | | HS Code | 2933992000 |
| | 6-FLUOROQUINAZOLIN-4-ONE Usage And Synthesis |
| Synthesis | General procedure for the synthesis of 6-fluoro-4-hydroxyquinazoline from 2-amino-5-fluorobenzoic acid and the compound (CAS: 77287-34-4): operate with reference to the reaction and post-processing of Example 5, substituting only the type of o-aminobenzoic acid derivative. The specific experimental results are detailed in Table 4. | | References | [1] Patent: EP1997812, 2008, A1. Location in patent: Page/Page column 8
[2] European Journal of Medicinal Chemistry, 2012, vol. 50, p. 264 - 273
[3] Molecules, 2006, vol. 11, # 6, p. 383 - 392
[4] Bioorganic and Medicinal Chemistry, 2007, vol. 15, # 11, p. 3768 - 3774
[5] Chemistry and Biodiversity, 2018, vol. 15, # 6, |
| | 6-FLUOROQUINAZOLIN-4-ONE Preparation Products And Raw materials |
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