TCO-PEG3-TCO manufacturers
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| | TCO-PEG3-TCO Basic information |
| | TCO-PEG3-TCO Chemical Properties |
| Boiling point | 633.7±55.0 °C(Predicted) | | density | 1.11±0.1 g/cm3(Predicted) | | solubility | Soluble in DMSO, DCM, DMF | | pka | 11.65±0.46(Predicted) | | form | Oil | | color | Colorless to light yellow |
| | TCO-PEG3-TCO Usage And Synthesis |
| Description | TCO-PEG3-TCO is a reagent containing TCO moiety at both ends of the molecule. TCO group specifically and efficiently reacts with tetrazine. The hydrophilic PEG linker increases the solubility of compounds in aqueous media. | | Uses | TCO-PEG3-TCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238. DOI:10.1016/j.apsb.2019.08.001 |
| | TCO-PEG3-TCO Preparation Products And Raw materials |
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