(4E)-TCO-PEG4-amine manufacturers
- (4E)-TCO-PEG4-amine
-
- $0.00 / 10mg
-
2024-03-21
- CAS:2243569-24-4
- Min. Order: 10mg
- Purity: >95.00%
- Supply Ability: 10mg
|
| | (4E)-TCO-PEG4-amine Basic information |
| | (4E)-TCO-PEG4-amine Chemical Properties |
| Boiling point | 517.1±50.0 °C(Predicted) | | density | 1.09±0.1 g/cm3(Predicted) | | solubility | Soluble in DMSO, DCM, DMF | | pka | 11.95±0.46(Predicted) |
| | (4E)-TCO-PEG4-amine Usage And Synthesis |
| Description | TCO-PEG4-amine is a heterobifunctional click chemistry reagent. Amine is very reactive with active NHS ester or with carboxylic acid in the presence of of activators suh as EDC. TCO moiety enable fast click chemistry with tetrazine molecule. | | Uses | TCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238. DOI:10.1016/j.apsb.2019.08.001 |
| | (4E)-TCO-PEG4-amine Preparation Products And Raw materials |
|