(4E)-TCO-PEG4-amine

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(4E)-TCO-PEG4-amine manufacturers

  • (4E)-TCO-PEG4-amine
  • (4E)-TCO-PEG4-amine pictures
  • 2025-06-07
  • CAS:2243569-24-4
  • Min. Order: 10mg
  • Purity: >95.00%
  • Supply Ability: 10mg
(4E)-TCO-PEG4-amine Basic information
Product Name:(4E)-TCO-PEG4-amine
Synonyms:(4E)-TCO-PEG4-amine;TCO-PEG4-amine
CAS:2243569-24-4
MF:C19H36N2O6
MW:388.5
EINECS:
Product Categories:peg
Mol File:2243569-24-4.mol
(4E)-TCO-PEG4-amine Structure
(4E)-TCO-PEG4-amine Chemical Properties
Boiling point 517.1±50.0 °C(Predicted)
density 1.09±0.1 g/cm3(Predicted)
solubility Soluble in DMSO, DCM, DMF
pka11.95±0.46(Predicted)
Safety Information
MSDS Information
(4E)-TCO-PEG4-amine Usage And Synthesis
DescriptionTCO-PEG4-amine is a heterobifunctional click chemistry reagent. Amine is very reactive with active NHS ester or with carboxylic acid in the presence of of activators suh as EDC. TCO moiety enable fast click chemistry with tetrazine molecule.
UsesTCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
IC 50PEGs
References[1] Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238. DOI:10.1016/j.apsb.2019.08.001
(4E)-TCO-PEG4-amine Preparation Products And Raw materials
Tag:(4E)-TCO-PEG4-amine(2243569-24-4) Related Product Information
BDP fl-PEG4-(4E)-TCO Gly-PEG3-(4E)-TCO (4E)-TCO-PEG3-amine (2E)-TCO-PNB ester TCO-PEG4-NHS ester (4E)-TCO-PEG4-DBCO (4E)-TCO-amine TCO-PEG4-Acid trans-Cyclooctene-maleimide Sulfo-Cy5-(4E)-TCO TCO-PEG3-Amine TCO-carbonate TCO/E- active ester (p-NPE) / equatorial