| Company Name: |
Clearsynth Labs Limited
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+91-22-26355700 |
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| Products Intro: |
Product Name:Deoxycholic-d4 Acid
CAS:112076-61-6
Remarks:CS-C-01407
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| Company Name: |
Quality Control Solutions Ltd.
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66853366 13670046396 |
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sales@chem-strong.com |
| Products Intro: |
Product Name:Deoxycholic acid-2,2,4,4-d4
CAS:112076-61-6
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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DEOXYCHOLIC-2,2,4,4-D4 ACID manufacturers
- Deoxycholic acid-d4
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- $342.00 / 10mg
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2026-01-04
- CAS:112076-61-6
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | DEOXYCHOLIC-2,2,4,4-D4 ACID Basic information |
| Product Name: | DEOXYCHOLIC-2,2,4,4-D4 ACID | | Synonyms: | DEOXYCHOLIC-2,2,4,4-D4 ACID;Deoxycholic acid-2,2,4,4-d4;Deoxycholic-d4 Acid;Deoxycholic acid-D;Deoxycholic Acid-[d4] (Solution);DEOXYCHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL;Deoxycholic Acid-d4 MaxSpec? Standard;2H4]-Deoxycholic acid | | CAS: | 112076-61-6 | | MF: | C24H40O4 | | MW: | 392.58 | | EINECS: | | | Product Categories: | Steroids & Hormones - 13C & 2H;Alphabetical Listings;DStable Isotopes;Labeled Bioactive Compounds;Stable Isotopes;Steroids | | Mol File: | 112076-61-6.mol |  |
| | DEOXYCHOLIC-2,2,4,4-D4 ACID Chemical Properties |
| Melting point | 171-174 °C | | Fp | 9℃ | | storage temp. | -20°C | | solubility | DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly) | | form | Solid | | color | White to Off-White | | InChIKey | KXGVEGMKQFWNSR-FCSCGBJGSA-N | | SMILES | [H][C@@]12[C@]([C@](CC([2H])([2H])[C@@H](O)C3([2H])[2H])(C)[C@]3([H])CC2)([H])C[C@H](O)[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC(O)=O | | CAS Number Unlabeled | 83-44-3 |
| Hazard Codes | Xn | | Risk Statements | 22-36/37/38 | | Safety Statements | 26-36 | | RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | | WGK Germany | 3 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral |
| | DEOXYCHOLIC-2,2,4,4-D4 ACID Usage And Synthesis |
| Description | Deoxycholic acid-d4 (DCA-d4) is intended for use as an internal standard for the quantification of DCA (Item Nos. 20756 | 18231) by GC- or LC-MS. DCA is a secondary bile acid that is formed via microbial transformation of cholic acid in the colon. It can be conjugated to glycine or taurine to produce glycodeoxycholic acid (GDCA; ) or taurodeoxycholic acid (TDCA; ), respectively, in hepatocytes. DCA (0.2% v/v) inhibits spore germination induced by taurocholic acid (TCA; ) in seven C. difficile strains, as well as inhibits growth and decreases the cytotoxicity of C. difficile culture supernatants to Vero cells when used at a concentration of 0.02% v/v. It inhibits ionizing radiation-induced p53-dependent transcription in a reporter assay using HCT116 cells when used at a concentration of 200 μM. Fecal and intestinal tissue levels of DCA are increased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet. Increased serum DCA levels have been found in patients with colorectal cancer. | | Uses | Deoxycholic-2,2,4,4-d4 Acid (CAS# 112076-61-6) is a useful isotopically labeled research compound. | | Definition | ChEBI: Deoxycholic acid-2,2,4,4-d4 is a deuterated compound and a deoxycholic acid. | | References | [1] RAJANI THANISSERY Casey M T Jenessa A Winston. Inhibition of spore germination, growth, and toxin activity of clinically relevant C. difficile strains by gut microbiota derived secondary bile acids[J]. Anaerobe, 2017, 45: Pages 86-100. DOI: 10.1016/j.anaerobe.2017.03.004
[2] D. QIAO. Deoxycholic acid suppresses p53 by stimulating proteasome-mediated p53 protein degradation.[J]. Carcinogenesis, 2001, 22 6 1: 957-964. DOI: 10.1093/carcin/22.6.957
[3] HONG LIN. Alterations of Bile Acids and Gut Microbiota in Obesity Induced by High Fat Diet in Rat Model[J]. Journal of Agricultural and Food Chemistry, 2019, 67 13: 3624-3632. DOI: 10.1021/acs.jafc.9b00249
[4] EKKEHARD BAYERD?RFFER . Increased serum deoxycholic acid levels in men with colorectal adenomas[J]. Gastroenterology, 1993, 104 1: Pages 145-151. DOI: 10.1016/0016-5085(93)90846-5 |
| | DEOXYCHOLIC-2,2,4,4-D4 ACID Preparation Products And Raw materials |
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