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D-Glucurone

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Products Intro: Product Name:D-Glucurono-3,6-Lactone
CAS:32449-92-6
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CAS:32449-92-6
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CAS:32449-92-6
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CAS:32449-92-6
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CAS:32449-92-6
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D-Glucurone Basic information
Product Name:D-Glucurone
Synonyms:D-Glucurono-6,3-lactone D-Glucuronic Acid Lactone D(+)-Glucurono-3,6-lactone D-(+)-Glucuronic acid γ-lactone Glucuronolactone;D-(+)-Glucuronolactone for synthesis;b-d-anhydroglucuronate;d-glucurono-gamma-lactone;D-Glucuronic acid, g-lactone;D-Glucorono-6,3-lactone;Glucorolactone;D(+)-Glucurono-3,6-lactone SynonyM: D-Glucurone
CAS:32449-92-6
MF:C6H8O6
MW:176.12
EINECS:251-053-3
Product Categories:Biochemistry;Glucose;Sugar Acids;Sugars;Dextrins、Sugar & Carbohydrates;Miscellaneous Natural Products;Carbohydrates & Derivatives;carbohydrate;bulk drug material, food addictive;Halogenated Heterocycles;API;32449-92-6
Mol File:32449-92-6.mol
D-Glucurone Structure
D-Glucurone Chemical Properties
Melting point 172-175 °C (lit.)
alpha 19 º (c=10, H2O)
Boiling point 227.71°C (rough estimate)
density 1,76 g/cm3
refractive index 18.5 ° (C=5, H2O)
storage temp. Store below +30°C.
solubility water: soluble25mg/mL, clear, colorless
pka11.96±0.60(Predicted)
form Crystals or Crystalline Powder
color White
Odorat 100.00 %. very mild mentholic
Odor Typementholic
Optical Rotation[α]24/D +18.8°, c = 8 in H2O
Water Solubility SOLUBLE
Merck 14,4467
BRN 83595
InChIKeyOGLCQHRZUSEXNB-IEPORWDDSA-N
LogP-3.457 (est)
CAS DataBase Reference32449-92-6(CAS DataBase Reference)
EPA Substance Registry SystemD-Glucuronolactone (32449-92-6)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 24/25-36-26
WGK Germany 2
RTECS LZ8930000
TSCA Yes
HS Code 29322980
MSDS Information
ProviderLanguage
D-Glucurone English
SigmaAldrich English
ACROS English
ALFA English
D-Glucurone Usage And Synthesis
Chemical Propertieswhite crystals or crystalline powder
UsesD-Glucurone is a glucuronic acid derivative. It is used for treating canine hepatitis.
UsesD-Glucurono-6,3-lactone is a glucuronic acid derivative studied for its effectiveness against canine hepatitis. It is utilized in the studies such as starting regent in the synthesis of 2,3,4,-tris(tert.-butyldimethysilyl) glucuronic acid trichloroethylester, required for the preparation of 1-O-acyl glucuronide of the anti-inflammatory drug ML-3000, synthesis of optically active glucopyranoses, synthesis of long-chain alkyl glucofuranosides.
DefinitionThe γ-lactone of glucuronic acid. Found in plant gums and animal connective tissues.
General DescriptionD-(+)-Glucuronic acid γ-lactone (Glucourono-γ-lactone, Glucurone or Glycurone) is a carbohydrate derivative. It converted into L-ascorbic acid in animals and human body. Its molecule contains two five-membered rings. Its crystal structure has been studied.
Purification MethodsDissolve the lactone or mixture of lactone and acid in H2O and concentrate on a steam bath until crystallisation begins. Cool rapidly to room temperature wih stirring. After 2hours the product is filtered off, washed with cold EtOH and dried to m 174-175o and [] D +19.8o (c 5.2, H2O). The amount of free acid can be obtained by titration of an ice-cold aqueous solution with standard alkali. It can be recrystallised from EtOH, EtOH/H2O or MeOH, and the highest recorded m is 180o. [Stacey J Chem Soc 1529 1939, Mehltretter et al. J Am Chem Soc 73 2424 1951, Beilstein 18 III/IV 3055, 18/5 V 33.]
D-Glucurone Preparation Products And Raw materials
Raw materialsDOWEX MAC-3 ION EXCHANGE RESIN-->D-Glucuronic acid
Tag:D-Glucurone(32449-92-6) Related Product Information
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