- delta-Valerolactone
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- $5.00 / 200KG
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2026-05-14
- CAS:542-28-9
- Min. Order: 1KG
- Purity: ≥98%
- Supply Ability: 2000mt/year
- Delta-Valerolactone
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- $0.00 / 200kg
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2026-04-22
- CAS:542-28-9
- Min. Order: 20kg
- Purity: 99%
- Supply Ability: 20 tons
Related articles - What is δ-valerolactone?
- δ-valerolactone, also known as 1,5-valerolactone, delta-valerolactone, tetrahydro-2H-2-pyrone, tetrahydro-o-pyrone, tetrahydro....
- Aug 23，2021
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| | delta-Valerolactone Chemical Properties |
| Melting point | -13 °C | | Boiling point | 230 °C | | density | 1.105 g/mL at 20 °C | | vapor density | 3.45 (vs air) | | vapor pressure | 8.8Pa at 20℃ | | refractive index | n20/D 1.457(lit.) | | Fp | 212 °F | | storage temp. | -20°C | | solubility | Chloroform, Ethyl Acetate, Methanol | | form | Liquid | | color | Clear colorless to pale yellow | | Water Solubility | miscible | | BRN | 106436 | | Stability: | Moisture Sensitive | | InChI | 1S/C5H8O2/c6-5-3-1-2-4-7-5/h1-4H2 | | InChIKey | OZJPLYNZGCXSJM-UHFFFAOYSA-N | | SMILES | O=C1CCCCO1 | | LogP | 0 at 23℃ | | CAS DataBase Reference | 542-28-9(CAS DataBase Reference) | | NIST Chemistry Reference | 2H-Pyran-2-one, tetrahydro-(542-28-9) | | EPA Substance Registry System | 2H-Pyran-2-one, tetrahydro- (542-28-9) |
| Hazard Codes | Xi | | Risk Statements | 41 | | Safety Statements | 26-39 | | RIDADR | UN1760 | | WGK Germany | 3 | | RTECS | LU3580000 | | Hazard Note | Irritant/Keep Cold | | TSCA | TSCA listed | | HazardClass | 8 | | HS Code | 29322090 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Eye Dam. 1 |
| | delta-Valerolactone Usage And Synthesis |
| Description | δ-valerolactone, also known as 1,5-valerolactone, delta-valerolactone, tetrahydro-2H-2-pyrone, tetrahydro-o-pyrone, tetrahydrocoumarin; the English name is Delta -Valerolactone, the abbreviated name is generally δ -VL or DVL, and the molecular formula is C5H802. | | Uses | Due to its good application flexibility, lower biological toxicity, more derivative compounds, easy polymerization and greatly increase the viscosity of coatings and other characteristics, delta-valerolactone is widely used in polyesters, polyurethanes, special solvents, and coatings. | | Preparation | In the first step, the 1,5-pentanediol raw material is fed into the drying tower for dehydration, to ensure that the water content is less than 1wt%, under optimized conditions, less than 0.5wt%, further optimization, less than 0.1wt%, further optimization situation , Less than 0.05wt%, that is, 500wppm; in the second step, the dried 1,5-pentanediol is mixed with hydrogen and then enters the vaporizer. The molar ratio of hydrogen to 1,5-pentanediol is 10-5:1 The third step will be vaporized 1,5-pentanediol and hydrogen into the dehydrogenation reactor, under the normal pressure of 0.1MPa, 230-270 conditions, under the action of the dehydrogenation catalyst, 1,5-pentanediol Alcohol is converted into δ-valerolactone, in which the yield of δ-valerolactone exceeds 98%, and the water content of the exported crude product is less than 0.5wt%. | | Chemical Properties | clear colorless to pale yellow liquid | | Uses | δ-Valerolactone is a compound commonly used to synthesize copolyesters by means of lipase-catalyzed ring opening polymerization. | | Uses | δ-Valerolactone (tetrahydro-2H-2-pyranone or δ VL) can be used as a monomer unit in the synthesis of poly(δ-valerolactone)s poly(conjugated ester)s via ring-opening polymerization.
It can also be used as a starting material in the synthesis of (+)-guadinomic acid , sodium δ-hydroxyvalerate , methyl δ-hydroxyvalerate , and 5-hydroxyvaleraldehyde. | | Definition | ChEBI: The simplest member of the class of delta-lactone that is tetrahydro-2H-pyran substituted by an oxo group at position 2. | | Preparation | There are three main pathways for the preparation of δ-Valerolactone from furfural: the cyclopentanone pathway, the furfuryl alcohol/tetrahydrofurfuryl alcohol-1,5-pentanediol pathway, and the tetrahydrofuran pathway. The specific process is shown in Figure 1.
 | | Synthesis Reference(s) | Canadian Journal of Chemistry, 52, p. 3651, 1974 DOI: 10.1139/v74-546
The Journal of Organic Chemistry, 48, p. 5160, 1983 DOI: 10.1021/jo00174a003
Journal of the American Chemical Society, 69, p. 1545, 1947 DOI: 10.1021/ja01198a517 | | Flammability and Explosibility | Non flammable | | Purification Methods | Purify the -lactone by repeated fractional distillation. IR: max 1750 (in CS2), 1732 (in CHCl3),1748 (in CCl4) and 1733 (in MeOH) cm-1 [Huisgen & Ott Tetrahedron 6 253 1959, Linstead & Rydon J Chem Soc 580 1933, Jones et al. Can J Chem 37 2007 1959]. [Beilstein 17 H 235, 17 II 287, 17 III/IV 4169,17/9 V 17.] | | References | [1] BREI V, VARVARIN A, PRUDIUS S. One-pot synthesis of δ-valerolactone from tetrahydrofurfuryl alcohol and δ-valerolactone amidation over Сu/ZnO-Al2O3 catalyst[C]. 2016: 0. DOI:10.15407/HFTP07.04.395.
[2] ROBSON F. STOREY Douglas C H. Copolymerization of ϵ-caprolactone and δ-valerolactone[J]. Macromolecular Symposia, 1991, 42-43 1: 185-193. DOI:10.1002/masy.19910420115.
[3] YA. V. SOLOVYOVA. Synthesis of δ-Valerolactone Using Stable Hydrogen Peroxide Derivatives[J]. Russian Journal of Organic Chemistry, 2022, 58 4: 480-483. DOI:10.1134/S1070428022040029.
[4] LIN Y, CHEN K, BAI T, et al. Carbenium-Based Cationic Ring-Opening Polymerization of CO2-Based Disubstituted δ-Valerolactone[J]. ACS Macro Letters, 2025, 86 1. DOI:10.1021/acsmacrolett.5c00005.
[5] PHORNWALAN NANTHANANON Yong K K. Effect of chain architecture and comonomer ratio on the biodegradability and thermal stability of biodegradable copolymers of l-lactide and δ-valerolactone†[J]. Green Chemistry, 2024, 26 4: Pages 2031-2043. DOI:10.1039/d3gc04140a.
[6] MASAHIRO YAMASHITA. Organolanthanide-Initiated Living Polymerizations of ε-Caprolactone, δ-Valerolactone, and β-Propiolactone[J]. Macromolecules, 1996, 29 5: 1798-1806. DOI:10.1021/ma951400n.
[7] K. N. HOUK. Why δ-Valerolactone Polymerizes and γ-Butyrolactone Does Not[J]. The Journal of Organic Chemistry, 2008, 73 7: 2674-2678. DOI:10.1021/jo702567v. |
| | delta-Valerolactone Preparation Products And Raw materials |
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