Carprofen NEW

Specification of Carprofen CAS 53716-49-7:

Carprofen is a non-steroidal anti-inflammatory drug (NSAID) used primarily in veterinary medicine, most commonly for dogs. It is a prescription medication marketed under various brand names, with Rimadyl being the most well-known.

Its primary function is to reduce pain and inflammation. Think of it as being similar to ibuprofen or naproxen for humans, but it is specifically formulated for dogs and is much safer for them than human NSAIDs.

How It Works (Mechanism of Action)

Carprofen works by inhibiting enzymes called cyclooxygenases (COX enzymes). These enzymes are responsible for producing prostaglandins, which are chemicals in the body that promote inflammation, fever, and pain.

By blocking these enzymes, Carprofen effectively:

• Reduces inflammation

  Alleviates pain

  Lowers fever

It is considered a "COX-2 selective" inhibitor, meaning it primarily targets the COX-2 enzyme associated with inflammation, while largely sparing the COX-1 enzyme that helps maintain normal functions in the stomach lining and kidneys. This selectivity is what helps make it safer for dogs than non-selective NSAIDs.

Primary Uses in Veterinary Medicine

Carprofen is prescribed by veterinarians to manage pain and inflammation associated with:

1. Osteoarthritis: It is widely used for long-term management of chronic joint pain and inflammation in dogs.

2. Post-Surgical Pain: It is frequently given after surgeries (like spays, neuters, or orthopedic procedures) to control pain and help with recovery.

3. Other Inflammatory Conditions: It can be used for soft tissue injuries or other painful conditions as determined by a veterinarian.

Important Considerations: Safety, Side Effects, and Warnings

While Carprofen is safe and effective for most dogs when used as prescribed, it is a powerful medication that requires careful veterinary supervision.

• Administration: It is available in tablets (chewable and non-chewable), caplets, and an injectable form. The injectable form is typically used in a clinical setting.

  Common Side Effects: These are usually mild but can include:

• Vomiting

  Diarrhea

  Decreased appetite

  Lethargy

• Serious Side Effects (require immediate veterinary attention):

• Gastrointestinal Ulcers: Signs include black, tarry stools, vomiting blood, or abdominal pain.

  Liver or Kidney Toxicity: Increased drinking/urination, yellowing of gums/skin (jaundice).

  Rare Skin Reactions

• Contraindications: It should not be used in:

• Dogs with known hypersensitivity to Carprofen or other NSAIDs.

  Dogs with pre-existing kidney, liver, or gastrointestinal bleeding issues.

  It should NEVER be given to cats, as it is highly toxic to them.

• Drug Interactions: It should not be used with other NSAIDs (e.g., aspirin, meloxicam, deracoxib) or corticosteroids (e.g., prednisone), as this significantly increases the risk of severe side effects like stomach ulcers.

Summary

Disclaimer: This information is for educational purposes only. Carprofen is a prescription medication that must be used under the direct guidance and supervision of a licensed veterinarian. Always follow your vet's dosage instructions and monitor your pet for any adverse reactions.

Package of Carprofen CAS 53716-49-7:

Application of Carprofen CAS 53716-49-7:

Carprofen is a non-steroidal anti-inflammatory drug (NSAID) commonly used in animals to combat pain and inflammation, particularly as associated with osteoarthritis.