Capsaicin

Price	$1
Package	1KG

Product Details

Product Name: Capsaicin	CAS No.: 404-86-4
Min. Order: 1G	Purity: 98%
Supply Ability: 100KG	Release date: 2019/07/06

AD68

Capsaicin Basic information

Application in Particular Diseases

Product Name:	Capsaicin
Synonyms:	(E)-8-METHYL-NON-6-ENOIC ACID 4-HYDROXY-3-METHOXY-BENZYLAMIDE;(E)-CAPSAICIN;(E)-N-([4-HYDROXY-3-METHOXYPHENYL]METHYL)8-METHYL-6-NONEAMIDE;(E)-N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYL-6-NONENAMIDE;CAPSAICIN;CAPSAICINE;CAPSAICIN, NATURAL;FEMA 3404
CAS:	404-86-4
MF:	C18H27NO3
MW:	305.41
EINECS:	206-969-8
Product Categories:	INORGANIC & ORGANIC CHEMICALS;Anilines, Aromatic Amines and Nitro Compounds;Miscellaneous Natural Products;Natural Plant Extract;Intermediates & Fine Chemicals;Pharmaceuticals;Vanilloid/TRPV channel;Amines;Aromatics;Alkaloid;Amides;Bioactive Small Molecules;Building Blocks;Carbonyl Compounds;C-CH;Cell Biology;Chemical Synthesis;Nutrition Research;Organic Building Blocks;Phytochemicals by Chemical Classification;Phytochemicals by Plant (Food/Spice/Herb);Zingiber officinale (Ginger);API;Herb extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;NEURELAN;natural product;food additive;Inhibitors
Mol File:	404-86-4.mol

Capsaicin Chemical Properties

Melting point	62-65 °C(lit.)
Boiling point	210-220 C
density	1.1037 (rough estimate)
refractive index	1.5100 (estimate)
FEMA	3404 \| CAPSAICIN
Fp	113 °C
storage temp.	2-8°C
solubility	H₂O: insoluble
Water Solubility	insoluble
Merck	14,1768
Stability:	Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	404-86-4(CAS DataBase Reference)
EPA Substance Registry System	6-Nonenamide, N-[(4-hydroxy-3-methoxyphenyl) methyl]-8-methyl-, (6E)-(404-86-4)

Safety Information

Hazard Codes	T,T+
Risk Statements	25-37/38-41-42/43-36/37/38
Safety Statements	22-26-28-36/39-45-36/37/39
RIDADR	UN 2811 6.1/PG 2
WGK Germany	3
RTECS	RA8530000
F	10-21
HazardClass	6.1(a)
PackingGroup	II
Hazardous Substances Data	404-86-4(Hazardous Substances Data)

Capsaicin Usage And Synthesis

Application in Particular Diseases	In Osteoarthritis: Capsaicin, an extract of red peppers that causes release and ultimately depletion of substance P from nerve fibers, has been beneficial in providing pain relief in OA when applied topically over affected joints. It may be used alone or in combination with oral analgesics or NSAIDs. To be effective, capsaicin must be used regularly, and it may take up to 2 weeks to work. It is well tolerated, but some patients experience temporary burning or stinging at the site of application. Patients should be warned not to get the cream in their eyes or mouth and to wash their hands after application. Application of the cream, gel, or lotion is recommended four times daily, but tapering to twice-daily application may enhance long-term adherence with adequate pain relief.
Chemical Properties	Off-White Crystalline Solid
Uses	A representative lot is a 5:1 E:Z mixture. It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.
Uses	K channel blocker; multiple sclerosis therapy
Uses	analgesic (topical), depletes Substance P, neurotoxic
Uses	Capsaicin analogue (C175680). It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.
Uses	Capsaicin is used in many topical ointments used to relieve the pain of peripheral neuropathy (treatment of pain in the nerve endings near the surface of the skin).
Uses	As a tool in neurobiological research.
Biological Activity	Prototypic vanilloid receptor agonist (pEC 50 values are 7.97 and 7.10 at rat and human VR1 receptors respectively). Excites a subset of primary afferent sensory neurons, with subsequent antinociceptive and anti-inflammatory effects. Reversibly inhibits aggregation of platelets. Also available as part of the Vanilloid TRPV1 Receptor Tocriset™ .

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates： Pharmaceutical intermediates; OLED intermediates;

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career henan chemical co