Z-VAD-FMK
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1G |
| Supply Ability: | 100KG |
| Update Time: | 2019-07-06 |
Product Details
| Product Name: Z-VAD-FMK | CAS No.: 187389-52-2 |
| Min. Order: 1G | Purity: 98% |
| Supply Ability: 100KG | Release date: 2019/07/06 |
AD68
| Z-VAD-FMK Basic information |
| Product Name: | Z-VAD-FMK |
| Synonyms: | Z-VADC(OME)-FMK;methyl (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-phenylmethoxycarbonylamino-butanoyl]amino]propanoyl]amino]-4-oxo-pentanoate;N-BENZYLOXYCARBONYL-VAL-ALA-ASP FLUOROMETHYL KETONE;Z-VAD-FLUOROMETHYLKETONE;Z-VAD-FMK;Z-VAD-FMK, METHYL ESTER;Z-VAD(OME)-FLUOROMETHYLKETONE;Z-VAD(OME)-FMK |
| CAS: | 187389-52-2 |
| MF: | C21H28FN3O7 |
| MW: | 453.46 |
| EINECS: | |
| Product Categories: | Caspases/Apoptosis;Caspase/Related Products;Apoptosis;peptides;API;Inhibitors |
| Mol File: | Mol File |
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| Z-VAD-FMK Chemical Properties |
| density | 1.214±0.06 g/cm3 (20 ºC 760 Torr) |
| Fp | 396.7℃ |
| storage temp. | −20°C |
| solubility | DMSO: 20 mg/mL |
| form | powder |
| color | white |
| InChIKey | MIFGOLAMNLSLGH-QOKNQOGYSA-N |
| Safety Information |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| Z-VAD-FMK Usage And Synthesis |
| Uses | Z-VAD(OMe)-FMK is a cell-permeable, competitive, and irreversible inhibitor of all caspases. Through this action, it inhibits cleavage of poly(ADP-ribose) polymerase, preventing apoptosis when used at 10-50 μM. It also blocks caspase-mediated apoptosis in vivo. Z-VAD(OMe)-FMK effectively prevents caspase action in inflammasomes.[Cayman Chemical] |
| Biological Activity | Cell-permeable, irreversible pan-caspase inhibitor. Inhibits caspase processing and apoptosis induction in tumor cells in vitro (IC 50 = 0.0015-5.8 mM). Active in vivo . |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: Zhengzhou High tech Zone, Henan Province, China
INQUIRY
杨俊青
sales@coreychem.com
sales@coreychem.com